Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 3/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616092 | 0.80 | ROCK2 (0.49) | KDM4DCASRPTGS1PTGS2ROCK2 | |
| SCHEMBL29214272 | 0.76 | PTGS1 (0.56) | KDM4DCASRPTGS1PTGS2ALDH1A1 | |
| SCHEMBL15270318 | 0.74 | KMT2A (0.47) | PTGS1PTGS2ALDH1A1KMT2AGAA | |
| SCHEMBL15270572 | 0.74 | KMT2A (0.47) | PTGS1PTGS2ALDH1A1KMT2AGAA | |
| SCHEMBL27575328 | 0.72 | SLC7A5 (0.44) | KDM4DCASRPTGS1PTGS2ALDH1A1 | |
| SCHEMBL27486840 | 0.72 | SLC7A5 (0.44) | KDM4DCASRPTGS1PTGS2ALDH1A1 | |
| SCHEMBL27679309 | 0.72 | SLC7A5 (0.43) | KDM4DCASRPTGS1PTGS2ALDH1A1 | |
| SCHEMBL2423553 | 0.71 | RAB9A (0.51) | ALDH1A1KDM4EKMT2AHPGDEPHX2 | |
| SCHEMBL2423557 | 0.71 | RAB9A (0.51) | ALDH1A1KDM4EKMT2AHPGDEPHX2 | |
| SCHEMBL17594628 | 0.70 | EED (0.55) | KDM4DALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180290976-A1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. | 2018-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180290976-A1 | LSD1 INHIBITORS AND USES THEREOF | KDM1B, KDM1A, KDM2A | KDM4D 33/4885CASR 4297/4885RBP4 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.