Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995776 | 0.82 | LDHA (0.52) | MEN1KMT2AALDH1A1GAAPARP10 | |
| SCHEMBL5411510 | 0.79 | MTNR1A (0.45) | MEN1KMT2AALDH1A1LMNATP53 | |
| SCHEMBL22209161 | 0.78 | TDP1 (0.43) | L3MBTL1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7806645 | 0.76 | ATM (0.50) | ATML3MBTL1TDP1ELANEMEN1 | |
| SCHEMBL8122364 | 0.76 | ATM (0.54) | ATML3MBTL1TDP1ELANEMEN1 | |
| SCHEMBL28170097 | 0.76 | ELANE (0.50) | ATML3MBTL1TDP1ELANEMEN1 | |
| SCHEMBL28193187 | 0.74 | ATM (0.45) | ATML3MBTL1TDP1ELANEMEN1 | |
| SCHEMBL11884465 | 0.74 | PARP10 (0.45) | L3MBTL1TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL2560281 | 0.73 | LDHA (0.65) | GAALDHAALOX15CYP1A2CYP2D6 | |
| SCHEMBL31086956 | 0.73 | ATM (0.55) | ATML3MBTL1TDP1ELANEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269763-A1 | CRTH2 receptor ligands for medicinal uses | 7TM PHARMA A/S (DK) | 2011-11-03 | — | — | US | disclosed |
| US-8022063-B2 | CRTH2 receptor ligands for medicinal uses | 7TM PHARMA A/S (DK) | 2011-09-20 | — | — | US | disclosed |
| EP-2336113-A1 | CRTH2 Receptor Ligands for Medical Use | 7TM Pharma A/S (DK) | 2011-06-22 | — | — | EP | disclosed |
| US-20090099189-A1 | CRTH2 Receptor Ligands For Medicinal Uses | 7TM PHARMA A/S (DK) | 2009-04-16 | — | — | US | disclosed |
| US-20080312220-A1 | Oxadiazole Derivatives with Crth2 Receptor Activity | 7TM PHARMA A/S (DK) | 2008-12-18 | — | — | US | disclosed |
| EP-1960376-A1 | OXADIAZOLE DERIVATIVES WITH CRTH2 RECEPTOR ACTIVITY | 7TM Pharma A/S (DK) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007062677-A1 | THIAZOLYL- AND PYRIMIDINYL-ACETIC ACIDS AND THEIR USE AS CRTH2 RECEPTOR LIGANDS | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007062678-A1 | PHENOXYACETIC ACID DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007062773-A1 | OXADIAZOLE DERIVATIVES WITH CRTH2 RECEPTOR ACTIVITY | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |
| EP-1758579-A1 | CRTH2 RECEPTOR LIGANDS FOR MEDICINAL USES | 7TM Pharma A/S (DK) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005115382-A1 | CRTH2 RECEPTOR LIGANDS FOR MEDICINAL USES | 7TM PHARMA A/S (DK) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312220-A1 | Oxadiazole Derivatives with Crth2 Receptor Activity | HRH2, HRH1, HRH3 | ATM 2595/4885L3MBTL1 4155/4885TDP1 4861/4885 |
| US-20090099189-A1 | CRTH2 Receptor Ligands For Medicinal Uses | HRH1, HRH2, HRH3 | ATM 2953/4885L3MBTL1 2606/4885TDP1 4874/4885 |
| US-20110269763-A1 | CRTH2 receptor ligands for medicinal uses | HRH1, HRH2, HRH4 | ATM 2755/4885L3MBTL1 2813/4885TDP1 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.