SCHEMBL2560281

SCHEMBL2560281

O=C(O)C(Oc1ccccc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.65
CYP1A2 P05177 1/20 0.48
GAA P10253 1/20 0.48
CYP2C9 P11712 1/20 0.48
PKM P14618 1/20 0.48
CYP2C19 P33261 1/20 0.48
CYP2D6 P10635 1/20 0.48
PPARG P37231 13/20 0.47
PPARA Q07869 11/20 0.47
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
ALOX15 P16050 1/20 0.43
SRC P12931 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6380944 0.91 LDHA (0.62) LDHACYP1A2GAACYP2C9PKM
SCHEMBL995776 0.87 LDHA (0.52) LDHACYP1A2GAACYP2C9PKM
SCHEMBL10970589 0.87 LDHA (0.52) LDHACYP1A2GAACYP2C9PKM
SCHEMBL4564099 0.87 LDHA (0.52) LDHACYP1A2GAACYP2C9PKM
SCHEMBL10335497 0.87 LDHA (0.52) LDHACYP1A2GAACYP2C9PKM
SCHEMBL11360869 0.85 LDHA (0.50) LDHACYP1A2GAACYP2C9PKM
SCHEMBL9331782 0.83 LDHA (0.48) LDHACYP1A2GAACYP2C9PKM
SCHEMBL10880781 0.83 KMT2A (0.55) LDHACYP1A2GAACYP2C9PKM
SCHEMBL20592934 0.82 LDHA (0.47) LDHACYP1A2GAACYP2C9PKM
SCHEMBL26134046 0.82 LDHA (0.52) LDHACYP1A2GAACYP2C9PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12447321-B2 Medicant eluting adjuncts and methods of using medicant eluting adjuncts CILAG GMBH INTERNATIONAL (CH) 2025-10-21 US disclosed
US-11839733-B2 Medicant eluting adjuncts and methods of using medicant eluting adjuncts CILAG GMBH INTERNATIONAL (CH) 2023-12-12 US disclosed
US-11826535-B2 Medicant eluting adjuncts and methods of using medicant eluting adjuncts CILAG GMBH INTERNATIONAL (CH) 2023-11-28 US disclosed
EP-3138589-B1 SURGICAL ADJUNCTS HAVING MEDICANTS CONTROLLABLY RELEASABLE THEREFROM ETHICON LLC (PR) 2023-08-09 EP disclosed
US-20230078145-A1 MEDICANT ELUTING ADJUNCTS AND METHODS OF USING MEDICANT ELUTING ADJUNCTS CILAG GMBH INTERNATIONAL (CH) 2023-03-16 US disclosed
CN-114957065-A Malonic acid dithioester compound, preparation method and application thereof 沈阳化工大学 2022-08-30 CN disclosed
CN-108348659-B Surgical adjunct having a medicant controllably releasable therefrom 伊西康有限责任公司 2021-09-03 CN disclosed
US-20210196936-A1 MEDICANT ELUTING ADJUNCTS AND METHODS OF USING MEDICANT ELUTING ADJUNCTS CILAG GMBH INTERNATIONAL (CH) 2021-07-01 US disclosed
US-20200155822-A1 MEDICANT ELUTING ADJUNCTS AND METHODS OF USING MEDICANT ELUTING ADJUNCTS ETHICON LLC 2020-05-21 US disclosed
US-10569071-B2 Medicant eluting adjuncts and methods of using medicant eluting adjuncts ETHICON LLC (US) 2020-02-25 US disclosed
EP-0729466-A1 PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS PARKE, DAVIS & COMPANY (US) 1996-09-04 EP disclosed
WO-1995014013-A1 PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS PARKE, DAVIS & COMPANY (US) 1995-05-26 WO disclosed
WO-1995014014-A2 PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS PARKE, DAVIS & COMPANY (US) 1995-05-26 WO disclosed
EP-0085115-B2 MODIFIED BLOCK COPOLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 1995-04-19 EP disclosed
US-5342348-A Stents having delivery matrices which provide for the controlled release of bioactive substances KAPLAN AARON V (US) 1994-08-30 US disclosed
WO-1994013268-A1 METHOD AND DEVICE FOR TREATING AND ENLARGING BODY LUMENS KAPLAN AARON V (US) 1994-06-23 WO disclosed
EP-0085115-B1 MODIFIED BLOCK COPOLYMER COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-07-05 EP disclosed
EP-0282052-A2 Polyphenylene ether resin composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-09-14 EP disclosed
US-4140520-A 3,5-Dichloropyridyl-2-oxy-phenoxy malonic acids and derivatives and herbicidal use thereof ISHIHARA SANGYO KAISHA LTD. (JP) 1979-02-20 US disclosed
US-4140520-A 3,5-Dichloropyridyl-2-oxy-phenoxy malonic acids and derivatives and herbicidal use thereof ISHIHARA SANGYO KAISHA LTD. (JP) 1979-02-20 US disclosed