Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.67 |
| ▸ | ATP4B | P51164 | 1/20 | 0.67 |
| ▸ | GUCY1B2 | O75343 | 13/20 | 0.59 |
| ▸ | GUCY1A2 | P33402 | 13/20 | 0.59 |
| ▸ | GUCY1A1 | Q02108 | 13/20 | 0.59 |
| ▸ | GUCY1B1 | Q02153 | 13/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801023 | 0.87 | CYP1A2 (0.76) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL2192513 | 0.86 | ATP4A (0.70) | ATP4AATP4BGUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL8565905 | 0.85 | GUCY1B2 (0.59) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL16399537 | 0.85 | GUCY1B2 (0.59) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL18570368 | 0.84 | GUCY1B2 (0.58) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL16403246 | 0.84 | GUCY1B2 (0.58) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL2195617 | 0.84 | ATP4A (0.81) | ATP4AATP4BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16402780 | 0.83 | GUCY1B2 (0.63) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL15631153 | 0.83 | GUCY1B2 (0.68) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL20528787 | 0.83 | ATP4A (0.46) | ATP4AATP4BGUCY1B2GUCY1A2GUCY1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018184976-A1 | SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND USE OF SAME | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-10-11 | — | — | WO | disclosed |