Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5179338 | 0.76 | ALDH1A1 (0.32) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29442969 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL29728536 | 0.74 | MAPT (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL5702769 | 0.74 | MAPT (0.41) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL7641205 | 0.73 | ALDH1A1 (0.33) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL5178593 | 0.73 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| SCHEMBL11319562 | 0.72 | WDR5 (0.51) | ALDH1A1HSD17B10TSHRTDP1WDR5 | |
| Hydrochloric Acid SCHEMBL6156302 | 0.72 | — | — | |
| SCHEMBL27381 | 0.72 | ALDH1A1 (0.32) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL21245428 | 0.71 | ALDH1A1 (0.38) | ALDH1A1HSD17B10CYP2A6TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110650965-B | Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-110650978-B | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2022-09-23 | — | — | CN | disclosed |
| US-11427608-B2 | Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2022-08-30 | — | — | US | disclosed |
| US-11155659-B2 | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-10-26 | — | — | US | disclosed |
| EP-3606967-B1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2021-08-11 | — | — | EP | disclosed |
| US-20210115080-A1 | DIHYDROCARBYL-SILYL-BRIDGED-1,3 DISUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-04-22 | — | — | US | disclosed |
| US-20200115478-A1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-04-16 | — | — | US | disclosed |
| EP-3606967-A1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC Global Technologies B.V. (NL) | 2020-02-12 | — | — | EP | disclosed |
| CN-110650965-A | Dihydrocarbyl-silyl-bridged-1, 3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-110650978-A | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | SABIC环球技术有限责任公司 | 2020-01-03 | — | — | CN | disclosed |
| WO-2018185173-A1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155659-B2 | Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization | RPS10, ARL1, OR10J3 | ALDH1A1 2338/4885HSD17B10 1993/4885CYP2A6 3132/4885 |
| US-20200115478-A1 | DIMETHYL-SILYL-BRIDGED-1-SUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | RPS10, ARL1, OR10J3 | ALDH1A1 2338/4885HSD17B10 1993/4885CYP2A6 3132/4885 |
| US-20210115080-A1 | DIHYDROCARBYL-SILYL-BRIDGED-1,3 DISUBSTITUTED-2-INDENYL METALLOCENE COMPLEXES FOR OLEFIN POLYMERIZATION | APOL1, ARL1, ZC3HAV1L | ALDH1A1 714/4885HSD17B10 211/4885CYP2A6 1816/4885 |
| US-11427608-B2 | Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization | APOL1, ARL1, ZC3HAV1L | ALDH1A1 714/4885HSD17B10 211/4885CYP2A6 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.