SCHEMBL2052908

SCHEMBL2052908

Oc1cccc2c1OCC2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.56
BCL2L1 Q07817 1/20 0.42
BAD Q92934 1/20 0.42
DRD2 P14416 3/20 0.41
DAO P14920 1/20 0.37
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPN P05981 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX5 P09917 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
PTGS1 P23219 1/20 0.36
PDE4A P27815 1/20 0.36
KDR P35968 1/20 0.36
KMT2A Q03164 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7517744 0.88 BCL2L1 (0.48) PARP1BCL2L1BADDRD2MEN1
SCHEMBL28507933 0.86 BCL2L1 (0.52) PARP1BCL2L1BADDRD2MEN1
SCHEMBL6577620 0.79 PARP1 (0.41) PARP1BCL2L1BADDRD2MEN1
SCHEMBL6700650 0.77 BCL2L1 (0.45) PARP1BCL2L1BADDRD2MEN1
SCHEMBL6465805 0.77
SCHEMBL2994306 0.75 SSTR4 (0.44)
SCHEMBL293877 0.74 PARP1 (0.52) PARP1DAOHTR2ASLC6A2SLC6A4
SCHEMBL13635655 0.74 PARP1 (0.52) PARP1DRD2DRD3HTR2ASLC6A2
SCHEMBL5542419 0.74 PARP1 (0.56) PARP1DAOHTR2ASLC6A2SLC6A4
SCHEMBL2007697 0.74 PARP1 (0.52) PARP1TDP1L3MBTL1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113975408-A Nano vaccine based on non-methylated CpG, preparation method and application 上海市肿瘤研究所 2022-01-28 CN claimed
US-5616232-A IMMERSING STEEL PLATE IN ACIDIC BATH CONTAINING ZINC AND CHROMIUM IONS AND A POLYOXYETHYLENE-SUBSTITUTED PHENOL DERIVATIVE, ELECTROPLATING NIPPON STEEL CORPORATION (JP) 1997-04-01 US claimed
EP-0025843-B1 PREPARATION OF MONOALKYL ETHERS OF HYDROXYPHENOLS AND THEIR TRANSFORMATION INTO HYDROXYCUMARANES BAYER AG (DE) 1985-06-19 EP claimed
US-4321204-A Preparation of certain 2-methyl-2,3-dihydro-benzofuran-7-ols BAYER AKTIENGESELLSCHAFT (DE) 1982-03-23 US claimed
EP-0001486-A2 Process for preparing 2,3-dihydro-2,2-dimethyl-7-benzofuranol and benzodioxole intermediate therefor FMC Corporation (US) 1979-04-18 EP claimed
US-20260124156-A1 PLANT-DERIVED EXTRACELLULAR VESICLE (EVS) COMPOSITIONS AND USES THEREOF EV BIOSOLUTIONS S P A (IT) 2026-05-07 US disclosed
EP-4705532-A1 POROUS METAL STRUCTURES INCORPORATING NANOPARTICLES Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2026-03-11 EP disclosed
EP-4234561-B1 ANTIVIRAL PRODRUGS AND NANOFORMULATIONS THEREOF UNIV NEBRASKA (US) 2026-02-11 EP disclosed
US-20250367134-A1 PERIPHERALIZATION OF CENTRALLY-ACTING CANNABINOID-1 RECEPTOR ANTAGONISTS BY NANOPARTICLES FOR THE TREATMENT METABOLIC RELATED CONDITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-12-04 US disclosed
EP-4210669-B1 PHARMACEUTICAL COMPOSITION IN THE FORM OF A HYDROGEL COMPRISING ORANGE-DERIVED EXTRACELLULAR VESICLES EVOBIOTECH S R L IN LIQUIDAZIONE (IT) 2025-08-20 EP disclosed
EP-4558623-A1 ENVELOPED VIRUS LIKE PARTICLES COMPRISING SARS-COV-2 S PROTEIN National Research Council of Canada (CA) 2025-05-28 EP disclosed
US-20250129033-A1 METAP2 INHIBITORS AND USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-04-24 US disclosed
EP-0001486-A2 Process for preparing 2,3-dihydro-2,2-dimethyl-7-benzofuranol and benzodioxole intermediate therefor FMC Corporation (US) 1979-04-18 EP disclosed
EP-0001486-A2 Process for preparing 2,3-dihydro-2,2-dimethyl-7-benzofuranol and benzodioxole intermediate therefor FMC Corporation (US) 1979-04-18 EP disclosed
US-4118400-A THERMAL REARRANGEMENT OF 2-ISOPROPYL-1.3-BENZODIOXOLE, ACID CATALYST FMC CORPORATION (US) 1978-10-03 US disclosed
US-4118400-A THERMAL REARRANGEMENT OF 2-ISOPROPYL-1.3-BENZODIOXOLE, ACID CATALYST FMC CORPORATION (US) 1978-10-03 US disclosed
US-4118400-A THERMAL REARRANGEMENT OF 2-ISOPROPYL-1.3-BENZODIOXOLE, ACID CATALYST FMC CORPORATION (US) 1978-10-03 US disclosed
US-4024277-A INSECTICIDE AND PESTICIDE FMC CORPORATION (US) 1977-05-17 US disclosed
US-4024277-A INSECTICIDE AND PESTICIDE FMC CORPORATION (US) 1977-05-17 US disclosed
US-4013774-A INSECTICIDAL N-THIO-SUBSTITUTED CARBAMATES OF DIHYDROBENZOFURANOLS CHEVRON RESEARCH COMPANY (US) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124156-A1 PLANT-DERIVED EXTRACELLULAR VESICLE (EVS) COMPOSITIONS AND USES THEREOF EXOSC10, EXOSC9, PHOSPHO1 PARP1 892/4885BCL2L1 2320/4885BAD 1902/4885
US-20250367134-A1 PERIPHERALIZATION OF CENTRALLY-ACTING CANNABINOID-1 RECEPTOR ANTAGONISTS BY NANOPARTICLES FOR THE TREATMENT METABOLIC RELATED CONDITIONS CNR1, CNR2, GPR119 PARP1 998/4885BCL2L1 3556/4885BAD 1103/4885
US-20250129033-A1 METAP2 INHIBITORS AND USES THEREOF METAP2, METAP1, SPINT2 PARP1 2900/4885BCL2L1 3156/4885BAD 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.