Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14669893 | 0.85 | PLA2G7 (0.65) | PLA2G7MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL3529772 | 0.85 | PLA2G7 (0.61) | PLA2G7MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL3038079 | 0.85 | PLA2G7 (0.65) | PLA2G7MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3529574 | 0.85 | PLA2G7 (0.65) | PLA2G7MAPTALDH1A1ALOX15MEN1 | |
| SCHEMBL5762561 | 0.80 | PLA2G7 (0.58) | PLA2G7MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL14662468 | 0.79 | PLA2G7 (0.58) | PLA2G7MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL851128 | 0.79 | PLA2G7 (0.54) | PLA2G7MAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL8906815 | 0.78 | PLA2G7 (0.59) | PLA2G7MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL4238370 | 0.78 | PLA2G7 (0.60) | PLA2G7MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16119591 | 0.77 | PLA2G7 (0.54) | PLA2G7MAPTALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018187414-A1 | INHIBITORS OF MTOR-RICTOR INTERACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-10-11 | — | — | WO | disclosed |