Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529581 | 0.85 | PLA2G7 (0.70) | PLA2G7NPC1RAB9AMAPTCYP3A4 | |
| SCHEMBL851128 | 0.82 | PLA2G7 (0.54) | PLA2G7NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL14669893 | 0.78 | PLA2G7 (0.65) | PLA2G7NPC1RAB9AMAPTCYP3A4 | |
| SCHEMBL3529574 | 0.78 | PLA2G7 (0.65) | PLA2G7NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL3038079 | 0.78 | PLA2G7 (0.65) | PLA2G7NPC1RAB9ACYP3A4CYP2C19 | |
| SCHEMBL14881017 | 0.76 | MEN1 (0.54) | PLA2G7NPC1RAB9AMAPTCYP3A4 | |
| SCHEMBL5762561 | 0.76 | PLA2G7 (0.58) | PLA2G7NPC1RAB9AMAPTCYP3A4 | |
| SCHEMBL8906815 | 0.74 | PLA2G7 (0.59) | PLA2G7NPC1RAB9AMAPTCYP3A4 | |
| SCHEMBL4238370 | 0.74 | PLA2G7 (0.60) | PLA2G7NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL16119591 | 0.73 | PLA2G7 (0.54) | PLA2G7NPC1RAB9AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | ABBVIE INC. | 2007-06-21 | — | — | US | claimed |
| US-7196200-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | claimed |
| US-20050159423-A1 | Antibacterial compounds | ABBOTT LABORATORIES | 2005-07-21 | — | — | US | claimed |
| US-7737159-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2010-06-15 | — | — | US | disclosed |
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | ABBVIE INC. | 2007-06-21 | — | — | US | disclosed |
| US-7196200-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | disclosed |
| US-20050159423-A1 | Antibacterial compounds | ABBOTT LABORATORIES | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, FDPS, PGLS | PLA2G7 2695/4885NPC1 1886/4885RAB9A 1565/4885 |
| US-20050159423-A1 | Antibacterial compounds | MRPL21, FDPS, PGLS | PLA2G7 2695/4885NPC1 1886/4885RAB9A 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.