Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.65 |
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529581 | 0.85 | PLA2G7 (0.70) | PLA2G7DHODHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3038079 | 0.81 | PLA2G7 (0.65) | PLA2G7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14669893 | 0.81 | PLA2G7 (0.65) | PLA2G7NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29740133 | 0.80 | GRM4 (0.51) | PLA2G7SCN1ASCN5ASCN8AALDH1A1 | |
| SCHEMBL27700307 | 0.78 | EGFR (0.56) | PLA2G7NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3529772 | 0.78 | PLA2G7 (0.61) | PLA2G7NPC1RAB9AALDH1A1GAA | |
| SCHEMBL2981886 | 0.76 | ALDH1A1 (0.61) | PLA2G7NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5762561 | 0.76 | PLA2G7 (0.58) | PLA2G7NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14662468 | 0.76 | PLA2G7 (0.58) | PLA2G7NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4601453 | 0.75 | PLA2G7 (0.47) | PLA2G7SCN1ASCN5ASCN8ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | ABBVIE INC. | 2007-06-21 | — | — | US | claimed |
| US-7196200-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | claimed |
| US-20050159423-A1 | Antibacterial compounds | ABBOTT LABORATORIES | 2005-07-21 | — | — | US | claimed |
| US-7737159-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2010-06-15 | — | — | US | disclosed |
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | ABBVIE INC. | 2007-06-21 | — | — | US | disclosed |
| US-7196200-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | disclosed |
| US-20050159423-A1 | Antibacterial compounds | ABBOTT LABORATORIES | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, FDPS, PGLS | PLA2G7 2695/4885DHODH 306/4885SCN1A 2873/4885 |
| US-20050159423-A1 | Antibacterial compounds | MRPL21, FDPS, PGLS | PLA2G7 2695/4885DHODH 306/4885SCN1A 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.