Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28717517 | 0.97 | GABRA1 (0.40) | GABRA1GABRB2POLBTOP2AKDM4E | |
| SCHEMBL7107160 | 0.97 | GABRA1 (0.40) | GABRA1GABRB2POLBTOP2AKDM4E | |
| Potassium Ion SCHEMBL29099219 | 0.97 | GABRA1 (0.40) | GABRA1GABRB2POLBTOP2AKDM4E | |
| SCHEMBL4895555 | 0.97 | GABRA1 (0.40) | GABRA1GABRB2POLBTOP2AKDM4E | |
| SCHEMBL239504 | 0.84 | POLB (0.41) | GABRA1GABRB2POLBKDM4EALDH1A1 | |
| SCHEMBL11764994 | 0.83 | POLB (0.40) | GABRA1GABRB2POLB | |
| SCHEMBL11498474 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2POLBTOP2AKDM4E | |
| SCHEMBL9253769 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2POLBAKR1B1MAPK1 | |
| SCHEMBL367941 | 0.81 | GABRA1 (0.44) | GABRA1GABRB2POLBKDM4EALDH1A1 | |
| SCHEMBL17165112 | 0.81 | POLB (0.41) | GABRA1GABRB2POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426347-B2 | Process for preparing high concentrations of magnesium and boron combination materials | ENVIROCHEM SOLUTIONS LLC (US) | 2013-04-23 | — | — | US | claimed |
| US-20110130313-A1 | PROCESS FOR PREPARING HIGH CONCENTRATIONS OF MAGNESIUM AND BORON COMBINATION MATERIALS | ENVIROCHEM SOLUTIONS LLC (US) | 2011-06-02 | — | — | US | claimed |