Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28717517 | 0.97 | GABRA1 (0.40) | GABRA1GABRB2POLBKDM4EALDH1A1 | |
| Potassium Ion SCHEMBL29099219 | 0.97 | GABRA1 (0.40) | GABRA1GABRB2POLBKDM4EALDH1A1 | |
| SCHEMBL2052960 | 0.97 | GABRA1 (0.40) | GABRA1GABRB2POLBKDM4EALDH1A1 | |
| SCHEMBL7107160 | 0.97 | GABRA1 (0.40) | GABRA1GABRB2POLBKDM4EALDH1A1 | |
| SCHEMBL11764994 | 0.86 | POLB (0.40) | GABRA1GABRB2POLB | |
| SCHEMBL27061 | 0.84 | POLB (0.41) | GABRA1GABRB2POLBDUSP5KDM4E | |
| SCHEMBL17165112 | 0.84 | POLB (0.41) | GABRA1GABRB2POLBDUSP5KDM4E | |
| SCHEMBL11143499 | 0.83 | KCNH2 (0.36) | GABRA1GABRB2 | |
| SCHEMBL878180 | 0.82 | IKBKB (0.33) | POLBDUSP5KDM4EALDH1A1MEN1 | |
| SCHEMBL87868 | 0.82 | THRA (0.40) | KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384496-A | Building protective coating for multi-solid waste concrete and preparation method thereof | 山东众森科技股份有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-116936163-A | High-elongation steel-cored aluminum strand and manufacturing process thereof | 宁夏瑞银有色金属科技有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116706057-A | Composite positive electrode material and preparation method and application thereof | 蜂巢能源科技股份有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116500227-A | Method for testing copper strip stress of lead frame for etching | 宁波兴业盛泰集团有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-116234081-A | Intelligent heating barrel, heating rod and preparation method | 东莞市固豪塑胶五金制品有限公司 | 2023-06-06 | — | — | CN | claimed |
| WO-2023035709-A1 | SURFACE HYDROPHOBIC MODIFIED MAGNESIUM-BASED FLY ASH POROUS SOUND ABSORBING MATERIAL AND PREPARATION METHOD THEREFOR | 山西大学 | 2023-03-16 | — | — | WO | claimed |
| CN-115180842-A | Low-carbon low-emission solid waste based cementing material and preparation method thereof | 涉县清漳水泥制造有限公司 | 2022-10-14 | — | — | CN | claimed |
| CN-114711246-A | Efficient and stable dichlorvos smoke agent and application thereof | 黑龙江森工农化有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-110698364-B | Method for synthesizing mono/dialkyl sodium benzenesulfonate | 太原理工大学 | 2022-06-21 | — | — | CN | claimed |
| CN-114606763-A | Electromagnetic shielding film based on carbon nanotube composite waterborne polyurethane | 浙江理工大学 | 2022-06-10 | — | — | CN | claimed |
| CN-111592887-B | Composite heavy metal stabilizing agent composition for heavy metal lead and cadmium polluted acid soil and preparation method thereof | 福建龙净环保股份有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-112210067-A | Catalyst for single-component polyurethane foam and preparation method thereof | 苏州思德新材料科技有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-112191272-A | Organosilicon foam catalyst and preparation method thereof | 苏州思德新材料科技有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-111592887-A | Composite heavy metal stabilizing agent composition for heavy metal lead and cadmium polluted acid soil and preparation method thereof | 福建龙净环保股份有限公司 | 2020-08-28 | — | — | CN | claimed |
| CN-111088026-A | Foaming agent and preparation method and application thereof | 中国石油天然气股份有限公司 | 2020-05-01 | — | — | CN | claimed |
| CN-110918427-A | Automobile forged part rust prevention method | 霍山汇能汽车零部件制造有限公司 | 2020-03-27 | — | — | CN | claimed |
| JP-2008529776-A | — | — | 2008-08-07 | — | — | JP | claimed |
| EP-1848525-A1 | NATURAL AND SYNTHETIC SODIUM SULFONATE EMULSIFIER BLENDS | Chemtura Corporation (US) | 2007-10-31 | — | — | EP | claimed |
| WO-2006089310-A1 | NATURAL AND SYNTHETIC SODIUM SULFONATE EMULSIFIER BLENDS | CHEMTURA CORPORATION (US) | 2006-08-24 | — | — | WO | claimed |
| US-20060183649-A1 | Natural and synthetic sodium sulfonate emulsifier blends | CHEMTURA CORPORATION | 2006-08-17 | — | — | US | claimed |