SCHEMBL9253769

SCHEMBL9253769

C=CCc1cccc(S(N)(=O)=O)c1CC=C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
POLB P06746 1/20 0.39
CA2 P00918 12/20 0.38
CA1 P00915 11/20 0.38
CA9 Q16790 10/20 0.38
CA12 O43570 6/20 0.37
CA7 P43166 4/20 0.37
CA6 P23280 3/20 0.37
CA14 Q9ULX7 3/20 0.37
CA5A P35218 3/20 0.37
CA5B Q9Y2D0 3/20 0.37
CA4 P22748 2/20 0.37
CYP2C9 P11712 1/20 0.37
CDK2 P24941 1/20 0.37
AKR1B1 P15121 1/20 0.36
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29982553 0.84 CA2 (0.45) GABRA1GABRB2POLBCA2CA1
SCHEMBL2298623 0.84 CA2 (0.45) GABRA1GABRB2POLBCA2CA1
SCHEMBL367941 0.83 GABRA1 (0.44) GABRA1GABRB2POLBAKR1B1MAPK1
SCHEMBL11498474 0.83 GABRA1 (0.41) GABRA1GABRB2POLBAKR1B1MAPK1
SCHEMBL11785647 0.83 GABRA1 (0.41) GABRA1GABRB2POLBCA2CA1
SCHEMBL2052960 0.81 GABRA1 (0.40) GABRA1GABRB2POLBCYP2C9AKR1B1
SCHEMBL7107164 0.81 GABRA1 (0.43) GABRA1GABRB2POLBAKR1B1MAPK1
Magnesium SCHEMBL2052962 0.81 GABRA1 (0.43) GABRA1GABRB2POLBAKR1B1MAPK1
SCHEMBL4895555 0.81 GABRA1 (0.40) GABRA1GABRB2POLBCYP2C9AKR1B1
Potassium Ion SCHEMBL29099219 0.81 GABRA1 (0.40) GABRA1GABRB2POLBCYP2C9AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1798751-A Coupling agents for mineral-filled elastomer compositions. GEN ELECTRIC (US) 2006-07-05 CN claimed
EP-0475707-B1 Hot-melt ink composition SEIKO EPSON CORP (JP) 1995-03-22 EP claimed
US-5230731-A (Di)alkylbenzenesulfonamide SEIKO EPSON CORPORATION (JP) 1993-07-27 US claimed
EP-0475707-A2 Hot-melt ink composition SEIKO EPSON CORPORATION (JP) 1992-03-18 EP claimed
JP-5009422-A None JP disclosed
CN-102432924-B Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2014-04-09 CN disclosed
CN-1798751-B Coupling agents for mineral-filled elastomer compositions. MOMENTIVE PERFORMANCE MAT INC 2013-06-19 CN disclosed
CN-101641226-B Rubber composition, method of making the same, and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2013-02-13 CN disclosed
CN-101180334-B Crosslinkable silane-terminated polymers and sealant compositions made therewith MOMENTIVE PERFORMANCE MAT INC (US) 2012-04-04 CN disclosed
CN-101151316-B Process for the production of crosslinked polymer employing low VOC-producing silane crosslinker and resulting crosslinked polymer MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-02-22 CN disclosed
CN-101180334-A Crosslinkable silane-terminated polymers and sealant compositions made therewith MOMENTIVE PERFORMANCE MAT INC (US) 2008-05-14 CN disclosed
EP-0475707-B1 Hot-melt ink composition SEIKO EPSON CORP (JP) 1995-03-22 EP disclosed
EP-0623657-A2 Hot melt jet ink composition MARKEM CORPORATION (US) 1994-11-09 EP disclosed
US-5354368-A Comprising a tall oil rosin having an acid number of at least 55 and a rheology modifier of a benzoic acid ester; adhesion; wear resistance; image sharpness MARKEM CORPORATION (US) 1994-10-11 US disclosed
US-5230731-A (Di)alkylbenzenesulfonamide SEIKO EPSON CORPORATION (JP) 1993-07-27 US disclosed
US-5230731-A (Di)alkylbenzenesulfonamide SEIKO EPSON CORPORATION (JP) 1993-07-27 US disclosed
JP-H059422-A HOT-MELT INK COMPOSITION SEIKO EPSON CORP 1993-01-19 JP disclosed
EP-0475707-A2 Hot-melt ink composition SEIKO EPSON CORPORATION (JP) 1992-03-18 EP disclosed
EP-0475707-A2 Hot-melt ink composition SEIKO EPSON CORPORATION (JP) 1992-03-18 EP disclosed