Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SNCA | P37840 | 3/20 | 0.62 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.54 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22800109 | 0.85 | MEN1 (0.60) | MEN1KMT2AGPR27NPC1RAB9A | |
| SCHEMBL25348939 | 0.83 | TMPRSS4 (0.55) | MEN1KMT2ASNCAGPR27MAPT | |
| SCHEMBL8178093 | 0.82 | GPR27 (0.76) | MEN1KMT2AGPR27NPC1RAB9A | |
| SCHEMBL15329133 | 0.80 | TMPRSS4 (0.61) | MEN1KMT2ASNCATMPRSS4ALDH1A1 | |
| SCHEMBL27964618 | 0.80 | SNCA (0.67) | MEN1KMT2ASNCAGPR27NPC1 | |
| SCHEMBL6544730 | 0.80 | SNCA (0.62) | MEN1KMT2ASNCAGPR27NPC1 | |
| SCHEMBL677811 | 0.80 | SNCA (0.67) | MEN1KMT2ASNCAGPR27NPC1 | |
| SCHEMBL6544935 | 0.80 | GPR27 (0.72) | MEN1KMT2ASNCAGPR27NPC1 | |
| SCHEMBL20529618 | 0.78 | MLYCD (0.70) | MEN1KMT2ASNCANPC1RAB9A | |
| SCHEMBL8122863 | 0.77 | HTT (0.67) | MEN1KMT2ASNCAGPR27NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399196-A1 | Hydrogen Bond Directed Photocatalytic Hydrodefluorination and Methods of Use Thereof | UNIV OKLAHOMA STATE (US) | 2020-12-24 | — | — | US | disclosed |
| WO-2018187336-A1 | HYDROGEN BOND DIRECTED PHOTOCATALYTIC HYDRODEFLUORINATION AND METHODS OF USE THEREOF | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2018-10-11 | — | — | WO | disclosed |