SCHEMBL20529776

SCHEMBL20529776

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nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
MAPT P10636 2/20 0.46
MME P08473 1/20 0.36
ACE P12821 1/20 0.36
CPA1 P15085 1/20 0.36
ACE2 Q9BYF1 1/20 0.36
FAAH O00519 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC6A5 Q9Y345 1/20 0.36
GRIK1 P39086 2/20 0.35
GRIK2 Q13002 2/20 0.35
FFAR1 O14842 1/20 0.32
CYP19A1 P11511 1/20 0.32
RXRA P19793 1/20 0.32
PPARG P37231 1/20 0.32
OXER1 Q8TDS5 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20529784 1.00 ALDH1A1 (0.46) ALDH1A1MAPTMMEACECPA1
SCHEMBL20529783 1.00 ALDH1A1 (0.46) ALDH1A1MAPTMMEACECPA1
SCHEMBL20529782 1.00 ALDH1A1 (0.46) ALDH1A1MAPTMMEACECPA1
SCHEMBL29425334 0.83 FAAH (0.41) ALDH1A1MAPTMMEACECPA1
SCHEMBL15542780 0.83 FAAH (0.41) ALDH1A1MAPTMMEACECPA1
SCHEMBL21248496 0.83 FAAH (0.41) ALDH1A1MAPTMMEACECPA1
SCHEMBL16095430 0.83 FAAH (0.41) ALDH1A1MAPTMMEACECPA1
SCHEMBL17079552 0.83 FAAH (0.41) ALDH1A1MAPTMMEACECPA1
SCHEMBL15201831 0.83 FAAH (0.41) ALDH1A1MAPTMMEACECPA1
SCHEMBL20529774 0.80 FAAH (0.49) MAPTFAAHSMN1; SMN2SLC6A5CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz Therapeutics, Inc. 2021-10-21 US claimed
EP-3606940-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz, LLC (US) 2020-02-12 EP claimed
WO-2018187499-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY BIONIZ, LLC (US) 2018-10-11 WO claimed
US-12600757-B2 Peptides inhibiting gamma-c-cytokine activity and methods of use Bioniz Therapeutics, Inc. (US) 2026-04-14 US disclosed
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz Therapeutics, Inc. 2021-10-21 US disclosed
EP-3606940-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY Bioniz, LLC (US) 2020-02-12 EP disclosed
WO-2018187499-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY BIONIZ, LLC (US) 2018-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600757-B2 Peptides inhibiting gamma-c-cytokine activity and methods of use IL15, IL2, IL15RA ALDH1A1 3007/4885MAPT 667/4885MME 2936/4885
US-20210324029-A1 STABLE MODULATORS OF GAMMA-C-CYTOKINE ACTIVITY IL2, IL2RA, GMFG ALDH1A1 3771/4885MAPT 2789/4885MME 3222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.