Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 11/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398790 | 1.00 | FFAR2 (0.56) | FFAR2CAPN1GRM1GRM5MEN1 | |
| SCHEMBL1916673 | 0.94 | FFAR2 (0.58) | FFAR2CAPN1GRM1GRM5MEN1 | |
| SCHEMBL1916679 | 0.94 | FFAR2 (0.58) | FFAR2CAPN1GRM1GRM5MEN1 | |
| SCHEMBL1917139 | 0.93 | FFAR2 (0.60) | FFAR2GRM1PIK3CAMTORNPC1 | |
| SCHEMBL1917134 | 0.93 | FFAR2 (0.60) | FFAR2GRM1PIK3CAMTORNPC1 | |
| SCHEMBL2051200 | 0.92 | FFAR2 (0.65) | FFAR2GRM1KMT2APIK3CAMTOR | |
| SCHEMBL2051198 | 0.92 | FFAR2 (0.65) | FFAR2GRM1KMT2APIK3CAMTOR | |
| SCHEMBL2398184 | 0.92 | FFAR2 (0.60) | FFAR2PIK3CAMTOR | |
| SCHEMBL2398198 | 0.92 | FFAR2 (0.60) | FFAR2PIK3CAMTOR | |
| SCHEMBL2400079 | 0.91 | FFAR2 (0.53) | FFAR2MEN1MAPTKMT2APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230477-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2011-09-22 | — | — | US | claimed |
| WO-2011076732-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING GASTROINTESTINAL DISORDERS | EUROSCREEN S.A. (BE) | 2011-06-30 | — | — | WO | claimed |
| WO-2010066682-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | EUROSCREEN S.A. (BE) | 2010-06-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230477-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS | CPT1A, LIPC, PC | FFAR2 295/4885CAPN1 4013/4885GRM1 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.