SCHEMBL20530601

SCHEMBL20530601

C#CCOc1ccc(N)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.52
EP300 Q09472 2/20 0.50
KAT8 Q9H7Z6 2/20 0.50
MAOB P27338 6/20 0.46
CYP3A4 P08684 2/20 0.42
CYP2A6 P11509 1/20 0.42
MAPT P10636 1/20 0.41
MAOA P21397 2/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
HDAC3 O15379 1/20 0.38
KAT2B Q92831 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
CA12 O43570 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20530607 0.89 CYP3A4 (0.49) IDO1EP300KAT8MAOBCYP3A4
SCHEMBL19038923 0.89 CYP3A4 (0.49) IDO1MAOBCYP3A4CYP2A6MAPT
SCHEMBL592709 0.82 IDO1 (0.52) IDO1EP300KAT8CYP3A4MAPT
SCHEMBL19038909 0.81 CYP3A4 (0.57) MAOBCYP3A4CYP2A6MAPTMAOA
SCHEMBL20530594 0.79 IDO1 (0.59) IDO1EP300KAT8MAOBCYP3A4
SCHEMBL1477239 0.77 MAOB (0.56) MAOBCYP3A4CYP2A6MAPTMAOA
SCHEMBL20530602 0.76 CA12 (0.50) MAOBCYP3A4CYP2A6MAPTMAOA
SCHEMBL1806065 0.76 IDO1 (0.62) IDO1EP300KAT8CYP3A4MAPT
SCHEMBL2664436 0.75 CYP3A4 (0.42) IDO1MAOBCYP3A4CYP2A6MAPT
SCHEMBL2650195 0.74 CA12 (0.44) MAOBCYP3A4CYP2A6MAPTLOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11117873-B2 Oxazine compound, composition, and cured product DIC CORPORATION (JP) 2021-09-14 US disclosed
US-11028059-B2 Oxazine compound, composition and cured product DIC CORPORATION (JP) 2021-06-08 US disclosed
CN-108368217-B Oxazine compound, composition and cured product DIC株式会社 2021-05-07 CN disclosed
CN-108368216-B Oxazine compound, composition and cured product DIC株式会社 2020-09-18 CN disclosed
US-20180362480-A1 OXAZINE COMPOUND, COMPOSITION, AND CURED PRODUCT DIC CORPORATION (JP) 2018-12-20 US disclosed
US-20180362477-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC CORPORATION (JP) 2018-12-20 US disclosed
EP-3388459-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC Corporation (JP) 2018-10-17 EP disclosed
EP-3388461-A1 OXAZINE COMPOUND, COMPOSITION, AND CURED PRODUCT DIC Corporation (JP) 2018-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028059-B2 Oxazine compound, composition and cured product KDM5A, WDR5, RNF5 IDO1 1533/4885EP300 982/4885KAT8 739/4885
US-20180362480-A1 OXAZINE COMPOUND, COMPOSITION, AND CURED PRODUCT KDM5A, WDR5, SMC4 IDO1 1479/4885EP300 836/4885KAT8 746/4885
US-11117873-B2 Oxazine compound, composition, and cured product KDM5A, WDR5, SMC4 IDO1 1479/4885EP300 836/4885KAT8 746/4885
US-20180362477-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT KDM5A, WDR5, RNF5 IDO1 1533/4885EP300 982/4885KAT8 739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.