Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530689 | 0.80 | MEN1 (0.41) | HSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL20530696 | 0.80 | MEN1 (0.41) | HSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL20530703 | 0.71 | CYP1A2 (0.43) | KDM4ELMNA | |
| SCHEMBL16726852 | 0.67 | CCR1 (0.42) | HSD17B10HTR1AKDM4EALDH1A1LMNA | |
| SCHEMBL16713122 | 0.67 | KDM4E (0.55) | HSD17B10HTR1AKDM4EALDH1A1LMNA | |
| SCHEMBL20530688 | 0.67 | KDM4E (0.55) | HSD17B10HTR1AKDM4EALDH1A1LMNA | |
| SCHEMBL16545821 | 0.65 | CCR1 (0.52) | KDM4ELMNAL3MBTL1 | |
| SCHEMBL20530717 | 0.64 | GRIN2B (0.39) | HSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL20530716 | 0.62 | LMNA (0.39) | KDM4EALDH1A1LMNA | |
| SCHEMBL21160628 | 0.62 | CYP1A2 (0.38) | HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388419-A1 | GLI1 INHIBITORS AND USES THEREOF | Leadiant Biosciences SA (CH) | 2018-10-17 | — | — | EP | claimed |
| EP-3388419-A1 | GLI1 INHIBITORS AND USES THEREOF | Leadiant Biosciences SA (CH) | 2018-10-17 | — | — | EP | disclosed |