Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950271 | 0.82 | CYP11B1 (0.44) | AVPR2AVPR1AADORA2B | |
| SCHEMBL27364397 | 0.75 | — | — | |
| SCHEMBL5779690 | 0.73 | — | — | |
| Iodide SCHEMBL27303018 | 0.73 | CYP19A1 (0.41) | ADORA2B | |
| SCHEMBL9497797 | 0.73 | ADORA2B (0.33) | ADORA2B | |
| Hydrochloric Acid SCHEMBL9443719 | 0.72 | ADORA2B (0.32) | ADORA2B | |
| SCHEMBL9038632 | 0.71 | CYP11B1 (0.46) | ADORA2BKDM4E | |
| SCHEMBL15202232 | 0.68 | ALDH1A1 (0.37) | ADORA2BKDM4E | |
| SCHEMBL9533398 | 0.68 | PPARG (0.35) | ADORA2BMAPTTHRB | |
| SCHEMBL13516912 | 0.67 | CYP11B1 (0.60) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844020-B1 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS AS STEROID NUCLEAR RECEPTOR LIGANDS | EXELIXIS INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-20110144128-A1 | Heterocyclic Carboxamide Compounds as Steroid Nuclear Receptors Ligands | EXELIXIS, INC. (US) | 2011-06-16 | — | — | US | disclosed |
| WO-2007024744-A2 | HETEROCYCLIC CARBOXAMIDE COMPOUNDS AS STEROID NUCLEAR RECEPTOR LIGANDS | EXELIXIS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
| EP-1233663-B1 | Via fill compositions for direct attach of devices and methods for applying same | IBM (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6518096-B2 | Interconnect assembly and Z-connection method for fine pitch substrates | FUJITSU LIMITED (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0653904-B1 | Via fill compositions for direct attach of devices and methods for applying same | IBM (US) | 2002-12-11 | — | — | EP | disclosed |
| EP-1233663-A2 | Via fill compositions for direct attach of devices and methods for applying same | International Business Machines Corporation (US) | 2002-08-21 | — | — | EP | disclosed |
| US-20020090754-A1 | Interconnect assembly and z-connection method for fine pitch substrates | FUJITSU LIMITED (JP) | 2002-07-11 | — | — | US | disclosed |
| US-6197122-B1 | THERMALLY DECOMPOSING ENCAPSULATION AND UNDERFILL TO PROVIDE RESIDUE ON ELECTRONIC COMPONENTS AND DISSOLVING RESIDUE IN POLAR OR BASIC SOLVENT TO EXPOSE ELECTRONIC COMPONENTS | CORNELL RESEARCH FOUNDATION, INC. | 2001-03-06 | — | — | US | disclosed |
| US-6194024-B1 | CONNECTING TWO CIRCUIT CARRIERS; FILLING HOLE WITH SOLDER SPHERE | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-02-27 | — | — | US | disclosed |
| US-5973033-A | CURED THERMOSETS FOR ENCAPSULATION AND UNDERFILL FOR ELECTRONIC COMPONENTS THAT ARE THERMALLY DECOMPOSABLE TO ALLOW REPAIR, REPLACEMENT, RECOVERY OR RECYCLING OF OPERATIVE ELECTRONIC COMPONENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5948922-A | CROSSLINKING THERMOSETTING RESINS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-09-07 | — | — | US | disclosed |
| US-5887345-A | Method for applying curable fill compositon to apertures in a substrate | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1999-03-30 | — | — | US | disclosed |
| US-5766670-A | Via fill compositions for direct attach of devices and methods for applying same | INTERNATIONAL BUSINESS MACHINES CORPORATION | 1998-06-16 | — | — | US | disclosed |
| US-5571593-A | CIRCUIT CARRIERS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0653904-A2 | Via fill compositions for direct attach of devices and methods for applying same | International Business Machines Corporation (US) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994004507-A1 | BASKET PORPHYRIN OXYGEN CARRIERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1994-03-03 | — | — | WO | disclosed |
| EP-0309844-B1 | PROCESS FOR THE PREPARATION OF CHLOROTHIOL FORMIATES | BASF Aktiengesellschaft (DE) | 1991-12-04 | — | — | EP | disclosed |
| EP-0309844-A1 | Process for the preparation of chlorothiol formiates | BASF Aktiengesellschaft (DE) | 1989-04-05 | — | — | EP | disclosed |
| US-4331582-A | Epoxy latent catalyst | HITCO (US) | 1982-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144128-A1 | Heterocyclic Carboxamide Compounds as Steroid Nuclear Receptors Ligands | NCOA1, NCOA2, NCOA3 | AVPR2 634/4885AVPR1A 415/4885ADORA2B 909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.