Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27381848 | 0.81 | ALDH1A1 (0.33) | ALDH1A1MAPK1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL11618755 | 0.78 | ALDH1A1 (0.43) | MAPTALDH1A1MAPK1RAB9AHTT | |
| SCHEMBL11867255 | 0.76 | ALDH1A1 (0.36) | MAPTALDH1A1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL11052393 | 0.76 | CYP11B1 (0.37) | MAPTALDH1A1LMNA | |
| SCHEMBL28007794 | 0.75 | MAPK1 (0.33) | ALDH1A1MAPK1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28060400 | 0.75 | LMNA (0.35) | ALDH1A1MAPK1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9467304 | 0.75 | LMNA (0.35) | MAPTALDH1A1MAPK1RAB9AADORA2B | |
| SCHEMBL16328893 | 0.75 | LMNA (0.37) | ALDH1A1MAPK1RAB9AADORA2BSMN1; SMN2 | |
| SCHEMBL5878432 | 0.75 | LMNA (0.49) | MAPTALDH1A1MAPK1RAB9AADORA2B | |
| SCHEMBL11617013 | 0.75 | LMNA (0.38) | MAPTALDH1A1MAPK1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1023221-C | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE POULENC SANTE (FR) | 1993-12-22 | — | — | CN | claimed |
| EP-0325512-B1 | PROCESS FOR THE PREPARATION OF 1-ALKYL-5-NITRO-IMIDAZOLES | RHONE-POULENC SANTE (FR) | 1993-01-20 | — | — | EP | claimed |
| US-4925949-A | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | claimed |
| CN-1035824-A | The preparation method of 1-alkyl-5-nitroimidazole | RHONE POULENC SANTE (FR) | 1989-09-27 | — | — | CN | claimed |
| US-4021442-A | Production of 1-alkyl-5-nitroimidazoles | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | claimed |
| JP-1213268-A | — | — | None | — | — | JP | disclosed |
| CN-1023221-C | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE POULENC SANTE (FR) | 1993-12-22 | — | — | CN | disclosed |
| CN-1023221-C | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE POULENC SANTE (FR) | 1993-12-22 | — | — | CN | disclosed |
| CN-1023221-C | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE POULENC SANTE (FR) | 1993-12-22 | — | — | CN | disclosed |
| US-4925949-A | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925949-A | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4925949-A | Process for preparing 1-alkyl-5-nitroimidazoles | RHONE-POULENC SANTE (FR) | 1990-05-15 | — | — | US | disclosed |
| EP-0325512-A1 | Process for the preparation of 1-alkyl-5-nitro-imidazoles | RHONE-POULENC SANTE (FR) | 1989-07-26 | — | — | EP | disclosed |
| EP-0043922-A1 | Process for preparing 1,2-dimethyl-5-nitroimidazole | BASF Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |
| US-4273783-A | BACTERICIDES, FUNGICIDES, ANTIPROTOZOA AGENTS | GRISSMAN CHEMICALS LIMITED (GB) | 1981-06-16 | — | — | US | disclosed |
| US-4065567-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4021442-A | Production of 1-alkyl-5-nitroimidazoles | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-4021442-A | Production of 1-alkyl-5-nitroimidazoles | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-4021442-A | Production of 1-alkyl-5-nitroimidazoles | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-3991200-A | Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds | AMERICAN CYANAMID COMPANY (US) | 1976-11-09 | — | — | US | disclosed |