SCHEMBL2053236

SCHEMBL2053236

Cc1ccc(-c2ccccc2)c(-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.44
AGTR2 P50052 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
AGT P01019 2/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 3/20 0.35
PSMB5 P28074 1/20 0.35
LMNA P02545 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
HDAC7 Q8WUI4 1/20 0.34
MAPT P10636 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30956037 0.87 AGTR1 (0.51) AGTR1AGTR2L3MBTL1MEN1KMT2A
SCHEMBL635 0.87 AGTR1 (0.51) AGTR1AGTR2L3MBTL1MEN1KMT2A
SCHEMBL8698703 0.87 AGTR1 (0.47) AGTR1AGTR2L3MBTL1KMT2AAGT
SCHEMBL27531698 0.85 AGTR1 (0.40) AGTR1AGTR2AGTALDH1A1TSHR
SCHEMBL31214399 0.83 AGTR1 (0.42) AGTR1AGTR2L3MBTL1MEN1KMT2A
SCHEMBL29931122 0.83 AGTR1 (0.44) AGTR1AGTR2AGTALDH1A1POLB
SCHEMBL27586872 0.83 AGTR1 (0.44) AGTR1AGTR2AGTALDH1A1POLB
SCHEMBL29931185 0.82 AGTR1 (0.44) AGTR1AGTR2L3MBTL1AGTALDH1A1
SCHEMBL588221 0.82 AGTR1 (0.44) AGTR1AGTR2L3MBTL1AGTALDH1A1
SCHEMBL27946136 0.82 AGTR1 (0.38) AGTR1AGTR2AGTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108679-A Preparation method of N- (triphenylmethyl) -5- (4' -methylbiphenyl-2-yl) tetrazole 南京法恩化学有限公司 2024-05-31 CN claimed
CN-113748099-B Preparation method of triphenylchloromethane 临海市华南化工有限公司 2024-07-05 CN disclosed
CN-118108679-A Preparation method of N- (triphenylmethyl) -5- (4' -methylbiphenyl-2-yl) tetrazole 南京法恩化学有限公司 2024-05-31 CN disclosed
CN-118108679-A Preparation method of N- (triphenylmethyl) -5- (4' -methylbiphenyl-2-yl) tetrazole 南京法恩化学有限公司 2024-05-31 CN disclosed
CN-113748099-A Preparation method of triphenylchloromethane 临海市华南化工有限公司 2021-12-03 CN disclosed
CN-101768035-B Method for preparing and recovering aromatic methyl diphenyl compound ZHEJIANG HUAHAI PHARM CO LTD 2013-11-27 CN disclosed
EP-2513046-A2 PROCESS FOR THE PREPARATION OF 4-BROMOMETHYL-[1,1'-BIPHENYL]-2'-CARBONITRILE SANOFI (FR) 2012-10-24 EP disclosed
WO-2011073703-A2 PROCESS FOR THE PREPARATION OF 4-BROMOMETHYL-[1,1'-BIPHENYL]-2'-CARBONITRILE SANOFI-AVENTIS (FR) 2011-06-23 WO disclosed
CN-101768035-A Method for preparing and recovering aromatic methyl diphenyl compound ZHEJIANG HUAHAI PHARM CO LTD 2010-07-07 CN disclosed