Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AGT | P01019 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL635 | 0.91 | AGTR1 (0.51) | AGTR1AGTR2ALDH1A1TSHRPOLB | |
| SCHEMBL30956037 | 0.91 | AGTR1 (0.51) | AGTR1AGTR2ALDH1A1TSHRPOLB | |
| SCHEMBL6532773 | 0.90 | AGTR1 (0.46) | AGTR1AGTR2ALDH1A1TSHRABCG2 | |
| SCHEMBL9383185 | 0.90 | AGTR1 (0.46) | AGTR1AGTR2ALDH1A1TSHRABCG2 | |
| SCHEMBL976147 | 0.88 | LMNA (0.47) | AGTR1AGTR2ALDH1A1TSHRPOLB | |
| SCHEMBL30316147 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2TSHRAGTKCNN4 | |
| SCHEMBL2053236 | 0.87 | AGTR1 (0.44) | AGTR1AGTR2ALDH1A1TSHRPOLB | |
| SCHEMBL9024777 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2TSHRAGTKCNN4 | |
| SCHEMBL8246839 | 0.86 | AGTR1 (0.50) | AGTR1AGTR2ALDH1A1POLBHTT | |
| SCHEMBL9262004 | 0.86 | AGTR1 (0.46) | AGTR1AGTR2ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583940-A | Method for preparing losartan potassium key intermediate | 润都制药(荆门)有限公司 | 2023-01-10 | — | — | CN | claimed |
| WO-2013072924-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTS AND INTERMEDIATES THEREOF. | ALKEM LABORATORIES LTD. (IN) | 2013-05-23 | — | — | WO | claimed |
| CN-115583940-A | Method for preparing losartan potassium key intermediate | 润都制药(荆门)有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-115583940-A | Method for preparing losartan potassium key intermediate | 润都制药(荆门)有限公司 | 2023-01-10 | — | — | CN | disclosed |
| WO-2013072924-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF ANGIOTENSIN II ANTAGONISTS AND INTERMEDIATES THEREOF. | ALKEM LABORATORIES LTD. (IN) | 2013-05-23 | — | — | WO | disclosed |
| CN-101481374-B | Method for removing trityl group of 1-trityl-5-(1,1'-biphenylyl-2 yl)-1H-tetrazole compound | ZHEJIANG HUAHAI PHARM CO LTD | 2013-01-09 | — | — | CN | disclosed |
| CN-101481374-B | Method for removing trityl group of 1-trityl-5-(1,1'-biphenylyl-2 yl)-1H-tetrazole compound | ZHEJIANG HUAHAI PHARM CO LTD | 2013-01-09 | — | — | CN | disclosed |
| CN-101481374-A | Method for removing trityl group of 1-trityl-5-(1,1'-biphenylyl-2 yl)-1H-tetrazole compound | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2009-07-15 | — | — | CN | disclosed |
| CN-101481374-A | Method for removing trityl group of 1-trityl-5-(1,1'-biphenylyl-2 yl)-1H-tetrazole compound | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2009-07-15 | — | — | CN | disclosed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |