Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | AGT | P01019 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931185 | 1.00 | AGTR1 (0.44) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL27873329 | 0.91 | AGTR1 (0.44) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL29931122 | 0.89 | AGTR1 (0.44) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL27586872 | 0.89 | AGTR1 (0.44) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL796 | 0.89 | AGTR1 (0.50) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL29404889 | 0.89 | AGTR1 (0.50) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL27631745 | 0.88 | AGTR1 (0.44) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL8698703 | 0.83 | AGTR1 (0.47) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL2053236 | 0.82 | AGTR1 (0.44) | AGTR1AGTR2AGTPOLBALDH1A1 | |
| SCHEMBL7196989 | 0.82 | AGTR1 (0.41) | AGTR1AGTR2POLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039279-A | Synthesis process of trityl olmesartan medoxomil | 浙江华洋药业有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-113666881-A | Synthesis method of mutagenic azide impurities in tetrazole sartan bulk drugs | 河南华商药业有限公司 | 2021-11-19 | — | — | CN | claimed |
| CN-101328167-B | Preparation method of losartan | BEIJING SECOND PHARMACEUTICAL CO LTD | 2012-04-25 | — | — | CN | claimed |
| EP-1753746-B8 | NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | ROTTAPHARM SPA (IT) | 2012-02-15 | — | — | EP | claimed |
| EP-2049527-A2 | PREPARATION OF IRBESARTAN | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2009-04-22 | — | — | EP | claimed |
| EP-1753746-A2 | NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | ROTTAPHARM S.P.A. (IT) | 2007-02-21 | — | — | EP | claimed |
| WO-2006073376-A2 | PREPARATION OF IRBESARTAN | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2006-07-13 | — | — | WO | claimed |
| WO-2005105789-A2 | NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | ROTTAPHARM S.P.A. (IT) | 2005-11-10 | — | — | WO | claimed |
| CN-119039279-A | Synthesis process of trityl olmesartan medoxomil | 浙江华洋药业有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-119039279-A | Synthesis process of trityl olmesartan medoxomil | 浙江华洋药业有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-114835689-B | Solvent-free method for preparing irbesartan | 浙江金立源药业有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-115197159-A | Preparation method of valsartan intermediate | 山东新时代药业有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-113717118-B | Synthesis process of valsartan | 安徽美诺华药物化学有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-113717118-A | Synthesis process of valsartan | 安徽美诺华药物化学有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-1082029-A | The pyridone that Biphenylmethyl replaces | BAYER AG (DE) | 1994-02-16 | — | — | CN | disclosed |
| US-5281604-A | Pharmaceuticals | AMERICAN CYANAMID COMPANY (US) | 1994-01-25 | — | — | US | disclosed |
| US-5210211-A | 4-(1H-PYRROL-1-YL) IMIDAZOLES WITH ANGIOTENSION II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| CN-1070912-A | Imidazopyridine derivatives and preparation method thereof | TANABE SEIYAKU CO (JP) | 1993-04-14 | — | — | CN | disclosed |
| WO-1993000341-A1 | 4-(1-H-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |
| CN-1048546-A | Substituted imidazo-fused 6 unit heterocycle as angiotensin II antagonism medicine | MERCK & CO INC (US) | 1991-01-16 | — | — | CN | disclosed |