Benzo[D]Oxazole

Benzo[D]Oxazole

SCHEMBL20533641

c1c[nH]cn1.c1ccc2ocnc2c1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
FKBP5 Q13451 1/20 0.45
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
CTNNB1 P35222 2/20 0.34
WNT3A P56704 2/20 0.34
NAMPT P43490 2/20 0.33
DYRK1A Q13627 2/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 2/20 0.31
KDM4E B2RXH2 3/20 0.31
HPGD P15428 3/20 0.31
HSD17B10 Q99714 3/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Oxazole SCHEMBL28300728 1.00 ALDH1A1 (0.45) ALDH1A1FKBP5NPC1RAB9ASMN1; SMN2
Quinoxaline SCHEMBL27809289 0.95 ALDH1A1 (0.41) ALDH1A1FKBP5NPC1RAB9ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL27681217 0.90 ALDH1A1 (0.36) ALDH1A1FKBP5DYRK1A
Benzo[D]Oxazole SCHEMBL3935480 0.82 CTNNB1 (0.41) ALDH1A1NPC1RAB9ASMN1; SMN2CTNNB1
Benzo[D]Oxazole SCHEMBL8888913 0.81 NPC1 (0.39) ALDH1A1NPC1RAB9ASMN1; SMN2CTNNB1
Benzo[D]Oxazole SCHEMBL2724328 0.81
Benzo[D]Oxazole SCHEMBL7903 0.81
Benzo[D]Oxazole SCHEMBL2385440 0.81 NPC1 (0.43) ALDH1A1NPC1RAB9ASMN1; SMN2CTNNB1
Benzo[D]Oxazole SCHEMBL27844655 0.81 NPC1 (0.43) ALDH1A1NPC1RAB9ASMN1; SMN2CTNNB1
Phenazine SCHEMBL28557583 0.79 ALDH1A1 (0.59) ALDH1A1FKBP5NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10892421-B2 Organic small molecule semiconducting chromophores for use in organic electronic devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-01-12 US disclosed
US-20180301634-A1 ORGANIC SMALL MOLECULE SEMICONDUCTING CHROMOPHORES FOR USE IN ORGANIC ELECTRONIC DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-10-18 US disclosed
CN-101563389-B Polymers comprising fused selenophene MERCK PATENT GMBH 2013-07-17 CN disclosed
CN-101490862-B Polymer blends and their use in organic light emitting devices MERCK PATENT GMBH 2013-03-13 CN disclosed
CN-102150086-A Copolymer for electronic devices MERCK PATENT GMBH 2011-08-10 CN disclosed
CN-102150087-A Organic material and electrophotographic device MERCK PATENT GMBH 2011-08-10 CN disclosed
CN-101730948-A organic electroluminescent element IDEMITSU KOSAN CO 2010-06-09 CN disclosed
CN-101563389-A Polymers comprising fused selenophene MERCK PATENT GMBH (DE) 2009-10-21 CN disclosed
CN-101511902-A Konjugierte polymere, deren darstellung und verwendung MERCK PATENT GMBH (DE) 2009-08-19 CN disclosed
CN-101495535-A Copolymers of indenofluorene and thiophene MERCK PATENT GMBH (DE) 2009-07-29 CN disclosed
CN-101490044-A 1,4-bis(2-thienylvinyl)benzol derivatives and their use MERCK PATENT GMBH (DE) 2009-07-22 CN disclosed
CN-101490862-A Polymer blends and their use in organic light emitting devices MERCK PATENT GMBH (DE) 2009-07-22 CN disclosed
CN-101443928-A Indenofluorene polymer based organic semiconductor materials MERCK PATENT GMBH (DE) 2009-05-27 CN disclosed
CN-101418220-A Liquid crystalline medium MERCK PATENT GMBH (DE) 2009-04-29 CN disclosed
CN-101331558-A Conjugated polymers, their preparation and use MERCK PATENT GMBH (DE) 2008-12-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10892421-B2 Organic small molecule semiconducting chromophores for use in organic electronic devices PPOX, OCIAD2, CRY2 ALDH1A1 1741/4885FKBP5 2065/4885NPC1 4408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.