Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20533913 | 0.91 | CRHR1 (0.30) | ALDH1A1CRHR1 | |
| SCHEMBL20533569 | 0.87 | CRHR1 (0.44) | ALDH1A1CRHR1MAPT | |
| SCHEMBL20533764 | 0.87 | SMPD3 (0.34) | ALDH1A1MAPT | |
| SCHEMBL20533910 | 0.84 | CRHR1 (0.36) | ALDH1A1CRHR1MAPT | |
| SCHEMBL20533672 | 0.84 | CRHR1 (0.40) | ALDH1A1CRHR1MAPT | |
| SCHEMBL20533933 | 0.82 | PDE10A (0.30) | — | |
| SCHEMBL20533759 | 0.80 | PI4KB (0.38) | ALDH1A1MAPT | |
| SCHEMBL20533936 | 0.78 | CRHR1 (0.43) | ALDH1A1CRHR1MAPT | |
| SCHEMBL20533772 | 0.76 | ALDH1A1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL20533898 | 0.75 | SMPD3 (0.48) | ALDH1A1CRHR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | UCB BIOPHARMA SPRL (BE) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | PI4KA, PI4K2B, PI4KB | ALDH1A1 3654/4885CRHR1 4351/4885MAPT 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.