Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20533896 | 0.90 | ALDH1A1 (0.40) | PI4KBALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL20533571 | 0.86 | PI4KB (0.50) | PI4KBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL20533594 | 0.84 | ALDH1A1 (0.36) | PI4KBALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL20533906 | 0.83 | PI4KB (0.45) | PI4KBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL20533928 | 0.82 | PI4KB (0.48) | PI4KBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL20533667 | 0.80 | ALDH1A1 (0.31) | ALDH1A1MAPT | |
| SCHEMBL20533927 | 0.76 | PI4KB (0.52) | PI4KBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL21628158 | 0.73 | PI4KB (0.59) | PI4KBALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL21628162 | 0.72 | PI4KB (0.73) | PI4KBALDH1A1HPGDUSP2HSD17B10 | |
| SCHEMBL20528890 | 0.72 | PI4KB (0.60) | PI4KBALDH1A1HPGDUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | UCB BIOPHARMA SPRL (BE) | 2018-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180298009-A1 | Fused Pyrazole Derivatives As Kinase Inhibitors | PI4KA, PI4K2B, PI4KB | PI4KB 3/4885ALDH1A1 3654/4885HPGD 3977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.