SCHEMBL2053388

SCHEMBL2053388

Cn1ccc2cc(-c3ccc(OCF)cc3-c3csc(N(C(=O)C(CC(=O)O)CC4CCOCC4)C4CC4)n3)cnc21

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 9/20 0.52
CHRNA7 P36544 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1916963 1.00 FFAR2 (0.52) FFAR2CHRNA7
SCHEMBL1916109 0.94 FFAR2 (0.59) FFAR2CHRNA7
SCHEMBL1916115 0.94 FFAR2 (0.59) FFAR2CHRNA7
SCHEMBL1917018 0.93 FFAR2 (0.55) FFAR2
SCHEMBL1917026 0.93 FFAR2 (0.55) FFAR2
SCHEMBL1917160 0.92 FFAR2 (0.53) FFAR2
SCHEMBL1917147 0.92 FFAR2 (0.53) FFAR2
SCHEMBL1916279 0.91 FFAR2 (0.56) FFAR2CHRNA7
SCHEMBL1916285 0.91 FFAR2 (0.56) FFAR2CHRNA7
SCHEMBL1916546 0.90 FFAR2 (0.62) FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110230477-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS EUROSCREEN S.A. (BE) 2011-09-22 US claimed
EP-2364297-A1 Compounds, pharmaceutical composition and methods for use in treating metabolic disorders Euroscreen S.A. (BE) 2011-09-14 EP claimed
WO-2011076732-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING GASTROINTESTINAL DISORDERS EUROSCREEN S.A. (BE) 2011-06-30 WO claimed
WO-2010066682-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS EUROSCREEN S.A. (BE) 2010-06-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230477-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS CPT1A, LIPC, PC FFAR2 295/4885CHRNA7 4184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.