SCHEMBL20534530

SCHEMBL20534530

N#CCc1c(F)c(F)cc(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.34
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA4 P22748 1/20 0.30
CA12 O43570 1/20 0.30
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanide SCHEMBL28001851 0.95 TRPV4 (0.32) TRPV4
Cyanate SCHEMBL27838660 0.93 CA1 (0.31) TRPV4CA1CA2CA4
SCHEMBL12599751 0.86
SCHEMBL24108197 0.85 TRPV4 (0.33) TRPV4
SCHEMBL27100882 0.85
SCHEMBL25788395 0.81 TRPV4 (0.46) TRPV4CYP11B1CYP11B2
SCHEMBL24147286 0.79
SCHEMBL1020839 0.78
SCHEMBL29517820 0.78 EGFR (0.32) CYP11B1CYP11B2
SCHEMBL7104591 0.78 EGFR (0.32) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230247901-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-08-03 US disclosed
US-20230240137-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-07-27 US disclosed
US-20230240137-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-07-27 US disclosed
US-20230225201-A1 Organic Light Emitting Diode and Device Comprising the Same NOVALED GMBH (DE) 2023-07-13 US disclosed
US-20230225201-A1 Organic Light Emitting Diode and Device Comprising the Same NOVALED GMBH (DE) 2023-07-13 US disclosed
US-20230225141-A1 Organic Compound of Formula (I) for Use in Organic Electronic Devices, an Organic Electronic Device Comprising a Compound of Formula (I) and a Display Device Comprising the Organic Electronic Device NOVALED GMBH (DE) 2023-07-13 US disclosed
US-20230225141-A1 Organic Compound of Formula (I) for Use in Organic Electronic Devices, an Organic Electronic Device Comprising a Compound of Formula (I) and a Display Device Comprising the Organic Electronic Device NOVALED GMBH (DE) 2023-07-13 US disclosed
WO-2023117748-A1 DISPLAY DEVICE COMPRISING A COMMON CHARGE GENERATION LAYER AND METHOD FOR MAKING THE SAME NOVALED GMBH (DE) 2023-06-29 WO disclosed
WO-2023117749-A1 CHARGE GENERATION LAYER COMPRISING A COMPOUND OF FORMULA (I), ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE COMPRISING THE CHARGE GENERATION LAYER AS WELL AS COMPOUNDS OF FORMULA (I) NOVALED GMBH (DE) 2023-06-29 WO disclosed
EP-4199096-A1 DISPLAY DEVICE COMPRISING A COMMON CHARGE GENERATION LAYER AND METHOD FOR MAKING THE SAME Novaled GmbH (DE) 2023-06-21 EP disclosed
WO-2021259785-A1 ORGANIC ELECTRONIC DEVICE COMPRISING A COMPOUND OF FORMULA (I), DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE AS WELL AS COMPOUNDS OF FORMULA (I) FOR USE IN ORGANIC ELECTRONIC DEVICES NOVALED GMBH (DE) 2021-12-30 WO disclosed
WO-2021250279-A1 ORGANIC LIGHT EMITTING DIODE AND DEVICE COMPRISING THE SAME NOVALED GMBH (DE) 2021-12-16 WO disclosed
US-11136296-B2 Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof BAYER AKTIENGESELLSCHAFT (DE) 2021-10-05 US disclosed
US-11136296-B2 Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof BAYER AKTIENGESELLSCHAFT (DE) 2021-10-05 US disclosed
WO-2020217129-A1 LIGHT EMITTING DEVICE, LIGHT EMITTING APPARATUS, ELECTRONIC DEVICE AND LIGHTING DEVICE 株式会社半導体エネルギー研究所 2020-10-29 WO disclosed
EP-3609869-A1 SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF Bayer Aktiengesellschaft (DE) 2020-02-19 EP disclosed
US-20200031775-A1 SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2020-01-30 US disclosed
US-20200031775-A1 SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2020-01-30 US disclosed
CN-110730776-A Substituted N-arylethyl-2-arylquinoline-4-carboxamides and their use 拜耳股份公司 2020-01-24 CN disclosed
WO-2018189011-A1 SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2018-10-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200031775-A1 SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF AADAC, NAT1, EPX TRPV4 2318/4885CYP11B1 906/4885CYP11B2 295/4885
US-11136296-B2 Substituted N-arylethyl-2-arylquinoline-4-carboxamides and use thereof AADAC, NAT1, EPX TRPV4 2318/4885CYP11B1 906/4885CYP11B2 295/4885
US-20230240137-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices AOX1, CYP2C19, CYP2C9 TRPV4 1053/4885CYP11B1 169/4885CYP11B2 125/4885
US-20230247901-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices AOX1, CYP2C19, CYP2C9 TRPV4 851/4885CYP11B1 115/4885CYP11B2 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.