SCHEMBL20534691

SCHEMBL20534691

C[Si](C)(C)OC1O[C@H](CO)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@H]1O[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 2/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ MAPT P10636 1/20 0.30
▸ AMY2A P04746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23704408 1.00 LGALS8 (0.31) LGALS8L3MBTL1MAPTAMY2A
SCHEMBL19306157 1.00 LGALS8 (0.31) LGALS8L3MBTL1MAPTAMY2A
SCHEMBL23352090 0.90 AMY2A (0.32) LGALS8L3MBTL1AMY2A
SCHEMBL13728774 0.89 LGALS8 (0.39) LGALS8AMY2A
SCHEMBL21517909 0.89 LGALS8 (0.39) LGALS8AMY2A
SCHEMBL16687789 0.89 LGALS8 (0.39) LGALS8AMY2A
SCHEMBL19317375 0.85 — —
SCHEMBL17540865 0.81 AMY2A (0.41) LGALS8L3MBTL1AMY2A
SCHEMBL931603 0.81 LGALS8 (0.32) LGALS8
SCHEMBL16518072 0.81 LGALS8 (0.32) LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180296507-A1 REDOX-ACTIVATED GLYCOCONJUGATED PROCHELATORS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2018-10-18 — — US disclosed
CN-105732733-A Novel glucose-based brain-targeting prodrug with locking function 四川大学 2016-07-06 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180296507-A1 REDOX-ACTIVATED GLYCOCONJUGATED PROCHELATORS SLC2A1, SLC2A2, SLC2A4 LGALS8 249/4885L3MBTL1 2450/4885MAPT 4380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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