⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16687497 | 0.89 | LGALS8 (0.37) | — | |
| SCHEMBL20089472 | 0.85 | FGF1 (0.30) | — | |
| SCHEMBL19306157 | 0.85 | LGALS8 (0.31) | — | |
| SCHEMBL23704408 | 0.85 | LGALS8 (0.31) | — | |
| SCHEMBL20534691 | 0.85 | LGALS8 (0.31) | — | |
| SCHEMBL19317371 | 0.83 | — | — | |
| SCHEMBL16687490 | 0.81 | — | — | |
| SCHEMBL26878979 | 0.78 | LGALS8 (0.35) | — | |
| SCHEMBL23352090 | 0.76 | AMY2A (0.32) | — | |
| SCHEMBL21517909 | 0.74 | LGALS8 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-09-07 | — | — | US | disclosed |