Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | PTPRF | P10586 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570831 | 0.87 | MAPT (1.00) | MAPTPTPRFPTPN2PTPN1PTPN11 | |
| Bromide SCHEMBL28010281 | 0.85 | MAPT (0.96) | MAPTPTPRFPTPN2PTPN1PTPN11 | |
| Hydrochloric Acid SCHEMBL1405413 | 0.85 | MAPT (0.96) | MAPTPTPRFPTPN2PTPN1PTPN11 | |
| Diethylamine SCHEMBL28410463 | 0.82 | MAPT (0.89) | MAPTPTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL9243455 | 0.82 | MAPT (0.89) | MAPTPTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL14713993 | 0.78 | MAPT (0.80) | MAPTPTPRFPTPN2PTPN1PTPN11 | |
| SCHEMBL14537303 | 0.78 | MAPT (0.80) | MAPTPTPRFPTPN2PTPN1PTPN11 | |
| Pyridine SCHEMBL61964 | 0.77 | LMNA (0.50) | MAPTL3MBTL1ALDH1A1TDP1GAA | |
| Nitrobenzene SCHEMBL3237422 | 0.75 | ALDH1A1 (0.73) | MAPTL3MBTL1HPGDALOX12ALDH1A1 | |
| SCHEMBL10489391 | 0.73 | MAPT (0.72) | MAPTHPGDALOX12ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018189199-A1 | PYRIDINIUM SALTS AND USES THEREOF | UNIVERSITY COLLEGE LONDON (GB) | 2018-10-18 | — | — | WO | disclosed |