Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534986 | 0.90 | NPC1 (0.57) | RAB9ANPC1TSHRNQO2HDAC2 | |
| SCHEMBL20534961 | 0.89 | NPC1 (0.48) | RAB9ANPC1TSHRNQO2ALDH1A1 | |
| SCHEMBL13699679 | 0.86 | NPC1 (0.55) | RAB9ANPC1TSHRALDH1A1MAPT | |
| SCHEMBL13699672 | 0.82 | KDM4E (0.50) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL13335707 | 0.81 | RAB9A (0.45) | RAB9ANPC1TSHRNQO2HDAC2 | |
| SCHEMBL5010323 | 0.81 | NPC1 (0.45) | RAB9ANPC1HDAC2ALDH1A1MAPT | |
| SCHEMBL20535696 | 0.80 | KDM4E (0.59) | RAB9ANPC1ALDH1A1MAPTKDM4E | |
| SCHEMBL20535047 | 0.80 | SLC9A1 (0.43) | RAB9ANPC1ALDH1A1MAPTGAA | |
| SCHEMBL13335705 | 0.79 | RAB9A (0.44) | RAB9ANPC1NQO2HDAC2ALDH1A1 | |
| SCHEMBL13335720 | 0.79 | RAB9A (0.44) | RAB9ANPC1NQO2HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | claimed |
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | disclosed |