SCHEMBL2053578

SCHEMBL2053578

C=CCOC(=O)CNC(C)(O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
TDP1 Q9NUW8 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
ALDH1A1 P00352 5/20 0.35
GAA P10253 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP3A4 P08684 1/20 0.34
LMNA P02545 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PKM P14618 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
EPHX2 P34913 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10603014 0.77 TSHR (0.46) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL19032528 0.76 TSHR (0.42) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL461716 0.76
SCHEMBL1276353 0.76 TSHR (0.47) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL5136229 0.75 SMN1; SMN2 (0.50) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL253364 0.75 TSHR (0.43) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL4541560 0.75 TSHR (0.47) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL15234474 0.75 TSHR (0.47) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL29152953 0.73 TSHR (0.46) TSHRTDP1SMN1; SMN2MAPTCACNA1B
SCHEMBL8824241 0.73 TSHR (0.50) TSHRTDP1SMN1; SMN2MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11191795-B2 Herbal compositions and methods for treating herpes CARRASCO NINO BEATRIZ EUGENIA (US) 2021-12-07 US disclosed
US-20200261522-A1 HERBAL COMPOSITIONS AND METHODS FOR TREATING HERPES CARRASCO NIÑO BEATRIZ EUGENIA (US) 2020-08-20 US disclosed
EP-2544662-B1 FOAMABLE FORMULATION NUVO PHARMACEUTICALS INC (CA) 2020-05-20 EP disclosed
US-10646441-B2 Foamable formulation NUVO PHARMACEUTICALS INC. (CA) 2020-05-12 US disclosed
US-20180147144-A1 FOAMABLE FORMULATION NUVO PHARMACEUTICALS INC. (CA) 2018-05-31 US disclosed
US-9861579-B2 Foamable formulation NUVO PHARMACEUTICALS INC. (CA) 2018-01-09 US disclosed
US-20150342871-A1 HIGHLY PERMEATING TERBINAFINE FORMULATION CRESCITA THERAPEUTICS INC. (CA) 2015-12-03 US disclosed
US-20150297518-A1 FOAMABLE FORMULATION THE BANK OF NOVA SCOTIA (CA) 2015-10-22 US disclosed
US-9107823-B2 Foamable formulation NUVO RESEARCH INC. (CA) 2015-08-18 US disclosed
US-9084754-B2 Highly permeating terbinafine formulation NUVO RESEARCH INC. (CA) 2015-07-21 US disclosed
WO-2000012662-A1 LIQUID HARD SURFACE CLEANER RINSE RHODIA INC. (US) 2000-03-09 WO disclosed
WO-1999060085-A1 LIQUID HARD SURFACE CLEANER RINSE RHODIA INC. (US) 1999-11-25 WO disclosed
US-5919980-A ULTRAFILTRATION RHODIA INC. (US) 1999-07-06 US disclosed
EP-0631605-B1 FOAMING COMPOSITION AND PROCESS FOR WELL TREATMENT CLEARWATER INC (US) 1999-04-28 EP disclosed
US-5654480-A ULTRAFILTRATION IN PRESENCE OF AN AMPHOTERIC SURFACTANT RHONE-POULENC SURFACTANTS & SPECIALTIES, L.P. (US) 1997-08-05 US disclosed
US-5591701-A MIXTURE OF AMPHOTERIC FOAM-GENERATING AGENT AND CATIONIC OR ANIONIC SURFACTANT CLEARWATER, INC. (US) 1997-01-07 US disclosed
WO-1996036427-A1 RECOVERY AND REUSE OF SURFACTANTS FROM AQUEOUS SOLUTIONS RHONE-POULENC SURFACTANTS & SPECIALTIES, L.P. (US) 1996-11-21 WO disclosed
US-5385206-A Amphoteric foaming agent, anionic surfactant, collapsing foam on acidification CLEARWATER, INC. (US) 1995-01-31 US disclosed
EP-0631605-A1 ITERATED FOAM PROCESS AND COMPOSITION FOR WELL TREATMENT CLEARWATER, INC. (US) 1995-01-04 EP disclosed
WO-1994017154-A1 ITERATED FOAM PROCESS AND COMPOSITION FOR WELL TREATMENT CLEARWATER, INC. (US) 1994-08-04 WO disclosed