Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535047 | 0.91 | SLC9A1 (0.43) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL20535274 | 0.81 | KDM4E (0.56) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL20535048 | 0.80 | KDM4E (0.55) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL20534896 | 0.80 | KDM4E (0.62) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL20535663 | 0.80 | KDM4E (0.55) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL20534986 | 0.80 | NPC1 (0.57) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL20535044 | 0.78 | KDM4E (0.61) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL20535529 | 0.77 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL20535671 | 0.77 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL17706812 | 0.77 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | claimed |
| WO-2018189683-A1 | BENZOFURAN DERIVATIVES FOR USE AS AMPK ACTIVATORS | UNIVERSITA' DI PISA (IT) | 2018-10-18 | — | — | WO | disclosed |