Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL504170 | 0.79 | CA12 (0.32) | CA12CA1CA9ALDH1A1PKM | |
| Trifluoroacetic Acid SCHEMBL22660281 | 0.77 | GAA (0.32) | CA12CA1CA9ALDH1A1PKM | |
| SCHEMBL1058967 | 0.77 | — | — | |
| SCHEMBL18779 | 0.77 | — | — | |
| SCHEMBL14686081 | 0.77 | BRD4 (0.30) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL542504 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| Acetone SCHEMBL6550197 | 0.75 | GLA (0.35) | CA12CA1CA9 | |
| SCHEMBL30271302 | 0.74 | — | — | |
| Hydrogen Sulfide SCHEMBL15467095 | 0.74 | — | — | |
| Iodide SCHEMBL2789427 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328578-A2 | NOSCAPINE AND NOSCAPINE ANALOGS AND THEIR USE IN TREATING INFECTIOUS DISEASES BY TUBULIN BINDING INHIBITION | Emory University (US) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010030582-A2 | NOSCAPINE AND NOSCAPINE ANALOGS AND THEIR USE IN TREATING INFECTIOUS DISEASES BY TUBULIN BINDING INHIBITION | EMORY UNIVERSITY (US) | 2010-03-18 | — | — | WO | disclosed |