Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL14917 | 0.82 | CA1 (0.38) | CA12CA1CA9PKMALDH1A1 | |
| Bicarbonate SCHEMBL6150295 | 0.82 | CA1 (0.38) | CA12CA1CA9PKMALDH1A1 | |
| Pivalate SCHEMBL10534446 | 0.81 | POLB (0.34) | CA12CA1CA9ALDH1A1 | |
| Oxalic Acid SCHEMBL9728851 | 0.79 | CA12 (0.37) | CA12CA1CA9PKMALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2053629 | 0.79 | CA12 (0.31) | CA12CA1CA9PKMALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL22660281 | 0.79 | GAA (0.32) | CA12CA1CA9PKMALDH1A1 | |
| SCHEMBL338264 | 0.79 | KDM4E (0.34) | CA12CA1CA9ALDH1A1 | |
| SCHEMBL1123 | 0.79 | — | — | |
| SCHEMBL785147 | 0.79 | — | — | |
| SCHEMBL4891780 | 0.77 | KDM4E (0.36) | CA12CA1CA9PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11867698-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2024-01-09 | — | — | US | disclosed |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2021-02-11 | — | — | US | disclosed |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2020-11-24 | — | — | US | disclosed |
| US-20180238912-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2018-08-23 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-9841426-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC (US) | 2017-12-12 | — | — | US | disclosed |
| US-9677115-B2 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2015-08-06 | — | — | US | disclosed |
| US-20120028285-A1 | Clickable cross-linker | NATIONAL SCIENCE FOUNDATION | 2012-02-02 | — | — | US | disclosed |
| WO-2012006603-A2 | CLICKABLE CROSS-LINKER | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20100233744-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. | 2010-09-16 | — | — | US | disclosed |
| EP-2064290-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| WO-2008076524-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2008-06-26 | — | — | WO | disclosed |
| US-7304168-B2 | Photo-caged fluorescent molecules | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2007-12-04 | — | — | US | disclosed |
| US-20050042662-A1 | Photo-caged fluorescent molecules | BOARD OF REGENTS (US) | 2005-02-24 | — | — | US | disclosed |
| EP-1337550-A2 | HEPATITIS C TRIPEPTIDE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002060926-A2 | HEPATITIS C TRIPEPTIDE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028285-A1 | Clickable cross-linker | MTCL3, SPPL2B, VIP | CA12 1390/4885CA1 599/4885CA9 2904/4885 |
| US-20180238912-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | CA12 1018/4885CA1 422/4885CA9 664/4885 |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | CA12 1018/4885CA1 422/4885CA9 664/4885 |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | CA12 1018/4885CA1 422/4885CA9 664/4885 |
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | GLG1, GBA3, MIA3 | CA12 3608/4885CA1 2870/4885CA9 4006/4885 |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | CA12 1018/4885CA1 422/4885CA9 664/4885 |
| US-11867698-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | CA12 1018/4885CA1 422/4885CA9 664/4885 |
| US-20050042662-A1 | Photo-caged fluorescent molecules | GJA1, GJB2, CBX7 | CA12 2847/4885CA1 2713/4885CA9 3119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.