Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28839191 | 0.98 | ALDH1A1 (0.41) | ALDH1A1TSHRATMTHRBMEN1 | |
| SCHEMBL10267707 | 0.89 | ATM (0.34) | ALDH1A1TSHRATMTHRBLMNA | |
| SCHEMBL866817 | 0.86 | MEN1 (0.33) | TSHRATMMEN1KMT2A | |
| SCHEMBL846905 | 0.86 | SMN1; SMN2 (0.34) | ALDH1A1TSHRATMMEN1KMT2A | |
| SCHEMBL17589272 | 0.86 | SMN1; SMN2 (0.34) | ALDH1A1TSHRATMMEN1KMT2A | |
| SCHEMBL10260787 | 0.85 | ATM (0.37) | ALDH1A1TSHRATMLMNAKDM4E | |
| SCHEMBL663919 | 0.85 | ATM (0.50) | ALDH1A1TSHRATMMEN1BLM | |
| SCHEMBL847892 | 0.84 | SMN1; SMN2 (0.36) | ALDH1A1TSHRATMMEN1KMT2A | |
| SCHEMBL10314811 | 0.83 | PRKCA (0.40) | ALDH1A1TSHRATMMEN1KMT2A | |
| SCHEMBL18415749 | 0.81 | ATM (0.32) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516504-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | International Business Machines Corporation (US) | 2012-10-31 | — | — | EP | disclosed |
| EP-2516503-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | International Business Machines Corporation (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078804-A1 | ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011078805-A1 | BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2011-06-30 | — | — | WO | disclosed |