Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17589272 | 0.88 | SMN1; SMN2 (0.34) | MEN1KMT2AATMTSHRMAPK1 | |
| SCHEMBL846905 | 0.88 | SMN1; SMN2 (0.34) | MEN1KMT2AATMTSHRMAPK1 | |
| SCHEMBL10267707 | 0.88 | ATM (0.34) | ATMTSHR | |
| SCHEMBL847892 | 0.83 | SMN1; SMN2 (0.36) | MEN1KMT2AATMTSHRMAPK1 | |
| SCHEMBL15692235 | 0.83 | ATM (0.33) | ATM | |
| SCHEMBL15581038 | 0.82 | PRKCA (0.40) | — | |
| SCHEMBL15581037 | 0.82 | PRKCA (0.40) | — | |
| SCHEMBL10260787 | 0.81 | ATM (0.37) | ATMTSHR | |
| SCHEMBL18415749 | 0.80 | ATM (0.32) | ATM | |
| SCHEMBL18256737 | 0.80 | ATM (0.33) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143369-B2 | Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305281-A1 | POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF | PFAS, PAM, PCNA | MEN1 2426/4885KMT2A 4165/4885ATM 3376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.