Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17189664 | 0.84 | CNR2 (0.49) | CNR2ACP3FFAR1FFAR4HPGD | |
| SCHEMBL16442475 | 0.82 | P2RX7 (0.42) | CNR2ACP3HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL21311456 | 0.82 | P2RX7 (0.42) | CNR2ACP3HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL21632043 | 0.79 | CNR2 (0.45) | CNR2ACP3PTGFRFFAR1FFAR4 | |
| SCHEMBL21631985 | 0.79 | CNR2 (0.45) | CNR2ACP3PTGFRFFAR1FFAR4 | |
| SCHEMBL27728236 | 0.79 | CPA3 (0.45) | CNR2SMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL16004213 | 0.78 | P2RX7 (0.42) | CNR2ACP3HPGDALDH1A1 | |
| SCHEMBL20534680 | 0.78 | PTGFR (0.43) | PTGFRFFAR1FFAR4SMN1; SMN2EPHX2 | |
| SCHEMBL20534572 | 0.78 | FFAR4 (0.45) | PTGFRFFAR1FFAR4HPGDSMN1; SMN2 | |
| SCHEMBL20534750 | 0.77 | CYP1A2 (0.43) | ACP3ALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189012-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |