SCHEMBL20537239

SCHEMBL20537239

C=CCOc1ccc2ccccc2c1O

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.62
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
PTPN22 Q9Y2R2 1/20 0.44
HSD17B10 Q99714 2/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA9 Q16790 2/20 0.43
LIG1 P18858 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5526140 0.81 HPGD (0.57) HPGDPOLBGAAPTPN22HSD17B10
SCHEMBL3816129 0.81 HPGD (0.60) HPGDPOLBGAAHSD17B10TSHR
SCHEMBL15413871 0.81 HPGD (0.59) HPGDPOLBGAAHSD17B10TSHR
SCHEMBL4372673 0.80 HPGD (0.58) HPGDPOLBGAAHSD17B10TSHR
SCHEMBL20554560 0.80 HPGD (0.58) HPGDPOLBGAAHSD17B10TSHR
SCHEMBL4252855 0.80 HPGD (0.71) HPGDPOLBGAAHSD17B10TSHR
SCHEMBL30618849 0.80 HPGD (0.58) HPGDPOLBGAATSHRMAPK1
SCHEMBL29235274 0.80 HPGD (0.58) HPGDPOLBGAAHSD17B10TSHR
SCHEMBL29956080 0.80 HPGD (0.58) HPGDPOLBGAAHSD17B10TSHR
SCHEMBL4371294 0.79 HPGD (0.56) HPGDHSD17B10TSHRMAPK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221500-A Preparation method of chloro aromatic compound 大连理工大学 2024-06-21 CN disclosed
CN-108368069-B Oxazine compound, composition and cured product DIC株式会社 2022-10-14 CN disclosed
CN-108473642-B Oxazine compound, composition and cured product DIC株式会社 2021-05-07 CN disclosed
US-10913725-B2 Oxazine compound, composition and cured product DIC CORPORATION (JP) 2021-02-09 US disclosed
US-10399312-B2 Oxazine compound, composition and cured product DIC CORPORATION (JP) 2019-09-03 US disclosed
US-20180362479-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC CORPORATION (JP) 2018-12-20 US disclosed
US-20180333941-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC CORPORATION (JP) 2018-11-22 US disclosed
EP-3401311-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC Corporation (JP) 2018-11-14 EP disclosed
EP-3392281-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT DIC Corporation (JP) 2018-10-24 EP disclosed
CN-108368069-A Oxazine compound, composition and cured product DIC株式会社 2018-08-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180333941-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT KDM5A, PSMB5, CUL5 HPGD 1322/4885POLB 2286/4885GAA 2221/4885
US-10913725-B2 Oxazine compound, composition and cured product PSMB5, KDM5A, CUL5 HPGD 1165/4885POLB 2399/4885GAA 2061/4885
US-20180362479-A1 OXAZINE COMPOUND, COMPOSITION AND CURED PRODUCT PSMB5, KDM5A, CUL5 HPGD 1165/4885POLB 2399/4885GAA 2061/4885
US-10399312-B2 Oxazine compound, composition and cured product KDM5A, PSMB5, CUL5 HPGD 1322/4885POLB 2286/4885GAA 2221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.