Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954814 | 0.82 | HPGD (0.40) | HPGDGAAALDH1A1KDM4ENPC1 | |
| SCHEMBL29954583 | 0.82 | HPGD (0.40) | HPGDGAAMAPK1ALDH1A1KDM4E | |
| SCHEMBL29956903 | 0.80 | ALOX5 (0.50) | HPGDGAAPOLBTSHRMAPK1 | |
| SCHEMBL20537239 | 0.80 | HPGD (0.62) | HPGDGAAPOLBTSHRMAPK1 | |
| SCHEMBL1642006 | 0.80 | ALOX5 (0.50) | HPGDGAAPOLBTSHRMAPK1 | |
| SCHEMBL2564466 | 0.78 | TSHR (0.40) | HPGDGAAPOLBTSHRMAPK1 | |
| SCHEMBL3816129 | 0.78 | HPGD (0.60) | HPGDGAAPOLBTSHRMAPK1 | |
| SCHEMBL7675242 | 0.77 | MAPT (0.42) | HPGDGAAALDH1A1KDM4EMAPT | |
| SCHEMBL15413871 | 0.77 | HPGD (0.59) | HPGDGAAPOLBTSHRMAPK1 | |
| SCHEMBL5667110 | 0.77 | NPC1 (0.56) | HPGDGAAALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |