Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816129 | 0.81 | HPGD (0.60) | HPGDGAAPOLBALDH1A1MAPT | |
| SCHEMBL20554560 | 0.80 | HPGD (0.58) | HPGDGAAPOLBNCEH1MAPT | |
| SCHEMBL30618849 | 0.80 | HPGD (0.58) | HPGDGAAPOLBNCEH1ALDH1A1 | |
| SCHEMBL20537239 | 0.80 | HPGD (0.62) | HPGDGAAPOLBTSHRCYP1A2 | |
| SCHEMBL4252855 | 0.80 | HPGD (0.71) | HPGDGAAPOLBALDH1A1KDM4E | |
| SCHEMBL29235274 | 0.80 | HPGD (0.58) | HPGDGAAPOLBNCEH1ALDH1A1 | |
| SCHEMBL5806322 | 0.80 | HPGD (0.51) | HPGDGAAALDH1A1KDM4EMAPT | |
| SCHEMBL6041665 | 0.80 | TSHR (0.51) | HPGDGAAALDH1A1KDM4EMAPT | |
| SCHEMBL4371294 | 0.79 | HPGD (0.56) | HPGDALDH1A1KDM4ETSHRCYP1A2 | |
| SCHEMBL3147510 | 0.79 | ALOX5 (0.51) | HPGDGAANCEH1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035131-A2 | FLUOROSURFACTANTS | Merck Patent GmbH (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003446-A2 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |