Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 13/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59950 | 0.80 | ADORA2B (0.48) | TSHRHTTADORA2BADORA2AALDH1A1 | |
| SCHEMBL6033611 | 0.77 | ADORA2B (0.52) | HTTADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL8519588 | 0.76 | TSHR (0.36) | TSHRHTTGSK3BADORA2BADORA2A | |
| SCHEMBL272518 | 0.76 | TSHR (0.39) | TSHRHTTGSK3BADORA2BADORA2A | |
| Phosphoric Acid SCHEMBL8500180 | 0.74 | ADORA2B (0.43) | TSHRHTTADORA2BADORA2AALDH1A1 | |
| SCHEMBL60159 | 0.68 | TSHR (0.46) | TSHRHTTGSK3BADORA2BADORA2A | |
| SCHEMBL10535020 | 0.66 | ADORA2B (0.47) | TSHRADORA2BADORA2AMEN1CYP2C19 | |
| Xanthine SCHEMBL692609 | 0.66 | ADORA2B (0.54) | TSHRADORA2BADORA2AHSD17B10HPGD | |
| SCHEMBL150603 | 0.62 | GAA (0.45) | TSHRALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL538419 | 0.61 | ADORA2B (0.57) | TSHRADORA2BADORA2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726603-A1 | BROWN FAT CELL COMPOSITIONS AND METHODS | Biorestorative Therapies, Inc. (US) | 2014-05-07 | — | — | EP | disclosed |
| WO-2013003595-A1 | BROWN FAT CELL COMPOSITIONS AND METHODS | BIORESTORATIVE THERAPIES, INC. (US) | 2013-01-03 | — | — | WO | disclosed |
| EP-2509992-A2 | TREATMENTS FOR GASTROINTESTINAL DISORDERS | Ironwood Pharmaceuticals, Inc. (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071927-A2 | TREATMENTS FOR GASTROINTESTINAL DISORDERS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-16 | — | — | WO | disclosed |
| WO-2004069172-A2 | MULTILINEAGE-INDUCIBLE CELLS AND USES THEREOF | The Government of the United States of America as represented by the Department of Veterans Affairs (US) | 2004-08-19 | — | — | WO | disclosed |
| EP-0894133-A2 | NEUROPEPTIDE Y RECEPTOR Y5 AND NUCLEIC ACID SEQUENCE | Bayer Corporation (US) | 1999-02-03 | — | — | EP | disclosed |
| WO-1997037998-A2 | NEUROPEPTIDE Y RECEPTOR Y5 AND NUCLEIC ACID SEQUENCE | BAYER CORPORATION (US) | 1997-10-16 | — | — | WO | disclosed |