Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22503036 | 0.81 | ALDH1A1 (0.38) | ALDH1A1RAB9AKDM4EGAAPKM | |
| SCHEMBL2053852 | 0.76 | KDM4E (0.52) | ALDH1A1RAB9AKDM4EGLAGAA | |
| SCHEMBL5772646 | 0.74 | NPC1 (0.38) | ALDH1A1RAB9AKDM4EGLAGAA | |
| SCHEMBL5771074 | 0.74 | CCR1 (0.38) | ALDH1A1RAB9AKDM4EGLAGAA | |
| SCHEMBL6217690 | 0.73 | HPGD (0.41) | ALDH1A1RAB9AKDM4EGLAGAA | |
| SCHEMBL19817523 | 0.73 | ALDH1A1 (0.35) | ALDH1A1RAB9AKDM4EGAAPKM | |
| SCHEMBL9722892 | 0.69 | KCNH2 (0.53) | KCNH2TLR7TLR8CYP19A1KDM5A | |
| SCHEMBL27845677 | 0.68 | KCNH2 (0.56) | KCNH2ALDH1A1KDM4ECYP19A1TDP1 | |
| SCHEMBL27972324 | 0.68 | KCNH2 (0.56) | KCNH2ALDH1A1KDM4ECYP19A1TDP1 | |
| SCHEMBL5492183 | 0.68 | TLR7 (0.46) | KCNH2TLR7TLR8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110150961-A1 | ANTI-INFECTIVE CATHETERS | ANGIOTECH INTERNATIONAL AG (CH) | 2011-06-23 | — | — | US | disclosed |
| EP-2254640-A2 | ANTI-INFECTIVE CATHETERS | ANGIOTECH INTERNATIONAL AG (CH) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009105484-A2 | ANTI-INFECTIVE CATHETERS | ANGIOTECH PHARMACEUTICALS, INC. (CA) | 2009-08-27 | — | — | WO | disclosed |
| US-5037980-A | Anxiolytic agents, hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110150961-A1 | ANTI-INFECTIVE CATHETERS | NACA, PUF60, POLR1C | KCNH2 1124/4885TLR7 407/4885TLR8 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.