SCHEMBL20539335

SCHEMBL20539335

C=CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)/C(F)=C/C=C(\F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20539337 1.00 THRB (0.35) THRB
SCHEMBL1445345 0.84 THRB (0.31) THRB
SCHEMBL1445343 0.84 THRB (0.31) THRB
SCHEMBL1445340 0.80
SCHEMBL1445344 0.80
SCHEMBL22126689 0.80 LMNA (0.38) THRB
SCHEMBL22151302 0.80 LMNA (0.38) THRB
SCHEMBL2118364 0.80 LMNA (0.38) THRB
SCHEMBL19643453 0.80 LMNA (0.38) THRB
SCHEMBL22151303 0.80 LMNA (0.38) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11352457-B2 Fluorine-containing compound having unsaturated bond, and surface modifier using the same TOSOH FINECHEM CORPORATION (JP) 2022-06-07 US disclosed
EP-3401298-B1 NOVEL FLUORINE-CONTAINING COMPOUND HAVING UNSATURATED BOND, AND SURFACE MODIFIER USING SAME TOSOH FINECHEM CORP (JP) 2021-09-08 EP disclosed
EP-3401298-A1 NOVEL FLUORINE-CONTAINING COMPOUND HAVING UNSATURATED BOND, AND SURFACE MODIFIER USING SAME Tosoh Finechem Corporation (JP) 2018-11-14 EP disclosed
US-20180305484-A1 NOVEL FLUORINE-CONTAINING COMPOUND HAVING UNSATURATED BOND, AND SURFACE MODIFIER USING THE SAME TOSOH FINECHEM CORPORATION (JP) 2018-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180305484-A1 NOVEL FLUORINE-CONTAINING COMPOUND HAVING UNSATURATED BOND, AND SURFACE MODIFIER USING THE SAME AFF1, AFF2, AFF4 THRB 2672/4885
US-11352457-B2 Fluorine-containing compound having unsaturated bond, and surface modifier using the same AFF1, AFF2, AFF4 THRB 2567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.