Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2047333 | 0.88 | EPHX2 (0.50) | EPHX2KDM5ACNR1BCHEACHE | |
| SCHEMBL2047864 | 0.86 | EPHX2 (0.51) | EPHX2KDM5ACNR1BCHEACHE | |
| SCHEMBL14007077 | 0.85 | L3MBTL1 (0.37) | EPHX2BCHEACHECHRM2CHRM1 | |
| SCHEMBL13785393 | 0.82 | BCHE (0.36) | EPHX2BCHEACHECHRM2CHRM1 | |
| SCHEMBL2045578 | 0.80 | EPHX2 (0.51) | EPHX2KDM5ACNR1BCHEACHE | |
| SCHEMBL23343387 | 0.80 | EPHX2 (0.70) | EPHX2KDM5ACNR1BCHEACHE | |
| SCHEMBL4925384 | 0.80 | EPHX2 (0.65) | EPHX2KDM5ACNR1ESR1KDM4C | |
| SCHEMBL2482309 | 0.80 | EPHX2 (0.70) | EPHX2KDM5ACNR1BCHEACHE | |
| SCHEMBL8704909 | 0.80 | EPHX2 (0.65) | EPHX2KDM5ACNR1ESR1KDM4C | |
| SCHEMBL21596652 | 0.80 | EPHX2 (0.70) | EPHX2KDM5ACNR1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381651-B1 | POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM | DOW CORNING TORAY CO LTD (JP) | 2011-06-29 | — | — | EP | disclosed |
| CN-101142279-B | Silicone emulsion, method of preparing same, and cosmetic ingredient | DOW CORNING | 2010-12-01 | — | — | CN | disclosed |
| EP-1858982-B1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | DOW CORNING (US) | 2008-08-27 | — | — | EP | disclosed |
| US-20080182833-A1 | Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient | DOW CORNING CORPORATION | 2008-07-31 | — | — | US | disclosed |
| CN-101142279-A | Silicone emulsion, method of preparing same, and cosmetic ingredient | DOW CORNING (US) | 2008-03-12 | — | — | CN | disclosed |
| EP-1858982-A1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | Dow Corning Corporation (US) | 2007-11-28 | — | — | EP | disclosed |
| US-7300648-B2 | Polyorganosiloxane emulsion composition and a cosmetic material made therefrom | DOWECORNING TORAY SILICONE, CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| WO-2006102010-A1 | SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT | DOW CORNING CORPORATION (US) | 2006-09-28 | — | — | WO | disclosed |
| CN-1247699-C | Polyorganosiloxane emulsion, process for producing the same, and material for cosmetic preparation | DOW CORNING TORAY SILICONE (JP) | 2006-03-29 | — | — | CN | disclosed |
| US-20040147647-A1 | Polyorganosiloxane micro-emulsion composition and raw material for cosmetics | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2004-07-29 | — | — | US | disclosed |
| US-20040138373-A1 | Polyorganosiloxane emulsion composition and a cosmetic material made therefrom | DOW TORAY CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| CN-1505663-A | Polyorganosiloxane emulsion composition and a cosmetic material made therefrom | ������������ʽ���� | 2004-06-16 | — | — | CN | disclosed |
| CN-1496387-A | Polyorganosiloxane emulsion, process for producing the same, and material for cosmetic preparation | 陶氏康宁东丽硅氧烷株式会社 | 2004-05-12 | — | — | CN | disclosed |
| EP-1406575-A2 | POLYORGANOSILOXANE MICRO-EMULSION COMPOSITION AND RAW MATERIAL FOR COSMETICS | Dow Corning Toray Silicone Co.,Ltd. Patent Department (JP) | 2004-04-14 | — | — | EP | disclosed |
| EP-1394215-A1 | POLYORGANOSILOXANE EMULSION, PROCESS FOR PRODUCING THE SAME, AND MATERIAL FOR COSMETIC PREPARATION | Dow Corning Toray Silicone Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-1381651-A1 | POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM | Dow Corning Toray Silicone Co.,Ltd. Patent Department (JP) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002094213-A2 | POLYORGANOSILOXANE MICRO-EMULSION COMPOSITION AND RAW MATERIAL FOR COSMETICS | DOW CORNING TORAY SILICONE CO.,LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002088253-A1 | POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2002-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182833-A1 | Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient | SQLE, CUTA, SMOX | EPHX2 516/4885KDM5A 1846/4885CNR1 3047/4885 |
| US-20040147647-A1 | Polyorganosiloxane micro-emulsion composition and raw material for cosmetics | UNG, PHOSPHO1, TPMT | EPHX2 1181/4885KDM5A 1407/4885CNR1 4050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.