Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG2 | P78540 | 6/20 | 0.46 |
| ▸ | ARG1 | P05089 | 5/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 4/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356218 | 0.89 | SLC7A5 (0.51) | SLC7A5CYP3A4SLC1A3HSD17B10ALPI | |
| SCHEMBL8319666 | 0.82 | CYP3A4 (0.48) | SLC7A5CYP3A4SLC1A3HSD17B10GRIA1 | |
| SCHEMBL849758 | 0.80 | SLC7A5 (0.51) | SLC7A5CYP3A4SLC1A3HSD17B10ALPI | |
| Methylamine SCHEMBL29022748 | 0.80 | CYP3A4 (0.46) | SLC7A5CYP3A4SLC1A3HSD17B10GRIA1 | |
| SCHEMBL27446953 | 0.77 | SLC7A5 (0.51) | SLC7A5CYP3A4SLC1A3HSD17B10ALPI | |
| SCHEMBL22403244 | 0.76 | SLC7A5 (0.50) | SLC7A5CYP3A4SLC1A3HSD17B10ALPI | |
| SCHEMBL29022740 | 0.75 | SLC7A5 (0.47) | SLC7A5CYP3A4SLC1A3HSD17B10ALPI | |
| SCHEMBL27264186 | 0.74 | SLC7A5 (0.49) | SLC7A5CYP3A4SLC1A3HSD17B10ALPI | |
| SCHEMBL10403754 | 0.73 | SLC7A5 (0.48) | SLC7A5CYP3A4SLC1A3HSD17B10ALPI | |
| SCHEMBL13095827 | 0.73 | SLC7A5 (0.54) | SLC7A5CYP3A4SLC1A3HSD17B10ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220296584-A1 | Membrane Active Molecules | KNOWLEDGE PHARMACEUTICALS INC. | 2022-09-22 | — | — | US | disclosed |
| EP-3973997-A1 | MEMBRANE ACTIVE MOLECULES | Branequest, Inc. (US) | 2022-03-30 | — | — | EP | disclosed |
| US-20200375958-A1 | MEMBRANE ACTIVE MOLECULES | KNOWLEDGE PHARMACEUTICALS INC. | 2020-12-03 | — | — | US | disclosed |
| EP-3615084-A1 | MEMBRANE ACTIVE MOLECULES | Branequest, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |
| WO-2018200412-A1 | MEMBRANE ACTIVE MOLECULES | BraneQuest, Inc. (US) | 2018-11-01 | — | — | WO | disclosed |
| US-20180303821-A1 | MEMBRANE ACTIVE MOLECULES | KNOWLEDGE PHARMACEUTICALS INC. | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220296584-A1 | Membrane Active Molecules | GABRP, GRIN3A, GRIN2A | ARG2 2061/4885ARG1 4334/4885SLC7A5 2297/4885 |
| US-20180303821-A1 | MEMBRANE ACTIVE MOLECULES | GABRP, GRIN3A, GRIN2A | ARG2 2061/4885ARG1 4334/4885SLC7A5 2297/4885 |
| US-20200375958-A1 | MEMBRANE ACTIVE MOLECULES | GABRP, GRIN3A, GRIN2A | ARG2 2061/4885ARG1 4334/4885SLC7A5 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.