Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.46 |
| ▸ | ITGAL | P20701 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.45 |
| ▸ | CDC25B | P30305 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22503688 | 1.00 | ITGB2 (0.46) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL30411705 | 0.89 | CTSS (0.42) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL22503768 | 0.84 | FOLH1 (0.50) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL22503648 | 0.83 | PTPN1 (0.52) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL20540507 | 0.83 | PRSS1 (0.48) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL22503717 | 0.83 | PRSS1 (0.48) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL503584 | 0.82 | TNF (0.53) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL503585 | 0.82 | TNF (0.53) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL27501725 | 0.82 | TNF (0.53) | ITGB2ICAM1ITGALPTPN1PTPN2 | |
| SCHEMBL692547 | 0.82 | CTSS (0.47) | ITGB2ICAM1ITGALPTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453699-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2022-09-27 | — | — | US | disclosed |
| US-20210054025-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | UNIV INDIANA RES & TECH CORP (US) | 2021-02-25 | — | — | US | disclosed |
| US-10793594-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2020-10-06 | — | — | US | disclosed |
| US-20180305402-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793594-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | CD47, CGAS, FPR1 | ITGB2 2174/4885ICAM1 57/4885ITGAL 2167/4885 |
| US-20180305402-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | CD47, CGAS, FPR1 | ITGB2 2174/4885ICAM1 57/4885ITGAL 2167/4885 |
| US-11453699-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | CD47, CGAS, FPR1 | ITGB2 2174/4885ICAM1 57/4885ITGAL 2167/4885 |
| US-20210054025-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | CD47, CGAS, FPR1 | ITGB2 2174/4885ICAM1 57/4885ITGAL 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.