Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | ITGAL | P20701 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503585 | 1.00 | TNF (0.53) | TNFKMT2ACTSSCTSKITGB2 | |
| SCHEMBL27501725 | 1.00 | TNF (0.53) | TNFKMT2ACTSSCTSKITGB2 | |
| SCHEMBL13956910 | 0.85 | KMT2A (0.54) | KMT2ACTSSCTSK | |
| SCHEMBL19355107 | 0.85 | KMT2A (0.57) | KMT2ACTSSCTSKLMNA | |
| SCHEMBL3006752 | 0.85 | CTSS (0.55) | KMT2ACTSSCTSKITGB2ICAM1 | |
| SCHEMBL19331886 | 0.85 | KMT2A (0.57) | KMT2ACTSSCTSKLMNA | |
| SCHEMBL692549 | 0.84 | CTSS (0.47) | KMT2ACTSSCTSKITGB2ICAM1 | |
| SCHEMBL692547 | 0.84 | CTSS (0.47) | KMT2ACTSSCTSKITGB2ICAM1 | |
| SCHEMBL8815317 | 0.83 | L3MBTL1 (0.52) | TNFKMT2ACTSSCTSKITGB2 | |
| SCHEMBL20540940 | 0.82 | ITGB2 (0.46) | CTSSCTSKITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11274126-B2 | pH-sensitive cyclic peptides | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2022-03-15 | — | — | US | claimed |
| EP-3432908-A1 | pH-SENSITIVE PEPTIDES | Rhode Island Council on Postsecondary Education (US) | 2019-01-30 | — | — | EP | claimed |
| WO-2017165452-A1 | pH-SENSITIVE PEPTIDES | RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (US) | 2017-09-28 | — | — | WO | claimed |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| US-12290575-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2025-05-06 | — | — | US | disclosed |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | UNIV NEW YORK (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240148911-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-05-09 | — | — | US | disclosed |
| US-20240075170-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-03-07 | — | — | US | disclosed |
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-02-08 | — | — | US | disclosed |
| EP-1950610-B1 | IMMERSION LITHOGRAPHIC COMPOSITION FOR FORMING UPPER FILM AND METHOD FOR FORMING PHOTORESIST PATTERN | JSR CORP (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-20120028198-A1 | UPPER LAYER-FORMING COMPOSITION AND PHOTORESIST PATTERNING METHOD | JSR CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20100003615-A1 | UPPER LAYER-FORMING COMPOSITION AND PHOTORESIST PATTERNING METHOD | JSR CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-1950610-A1 | COMPOSITION FOR FORMING UPPER FILM AND METHOD FOR FORMING PHOTORESIST PATTERN | JSR Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |
| CN-1160368-C | Endothelin antegon | 中国人民解放军军事医学科学院毒物药 | 2004-08-04 | — | — | CN | disclosed |
| CN-1155612-C | Endothelin antagon | 中国人民解放军军事医学科学院毒物药 | 2004-06-30 | — | — | CN | disclosed |
| CN-1155611-C | Endothelin antagon | 中国人民解放军军事医学科学院毒物药 | 2004-06-30 | — | — | CN | disclosed |
| CN-1330076-A | Endothelin antagon | INST OF TOXIC MEDICINES PLA S (CN) | 2002-01-09 | — | — | CN | disclosed |
| CN-1330077-A | Endothelin antegon | INST OF TOXIC MEDICINES PLA S (CN) | 2002-01-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274126-B2 | pH-sensitive cyclic peptides | VIP, PHLPP1, PHLPP2 | TNF 1289/4885KMT2A 4272/4885CTSS 2243/4885 |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | TNF 1499/4885KMT2A 4091/4885CTSS 4120/4885 |
| US-20240042063-A1 | LINKED AND OTHER pH-TRIGGERED COMPOUNDS | LIPA, PHOSPHO1, NGLY1 | TNF 492/4885KMT2A 4050/4885CTSS 522/4885 |
| US-20240075170-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | NPPA, LNPEP, VIP | TNF 243/4885KMT2A 4156/4885CTSS 657/4885 |
| US-20240148911-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | NPPA, LNPEP, VIP | TNF 243/4885KMT2A 4156/4885CTSS 657/4885 |
| US-12290575-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | NPPA, LNPEP, VIP | TNF 243/4885KMT2A 4156/4885CTSS 657/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | TNF 2310/4885KMT2A 2849/4885CTSS 4503/4885 |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | TNF 1495/4885KMT2A 3979/4885CTSS 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.