Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20542002 | 0.95 | MCHR1 (0.45) | HDAC1MCHR1SUCNR1FAAHS1PR1 | |
| SCHEMBL20541734 | 0.92 | FAAH (0.44) | HDAC1FAAHBACE1S1PR1S1PR3 | |
| SCHEMBL20542055 | 0.92 | RAB9A (0.46) | HDAC1HTR2CMCHR1FAAHS1PR1 | |
| SCHEMBL20541736 | 0.91 | NPC1 (0.49) | MCHR1FAAHS1PR1S1PR3GAA | |
| SCHEMBL20541739 | 0.90 | MEN1 (0.42) | MCHR1FAAHS1PR1S1PR3MEN1 | |
| SCHEMBL20541643 | 0.89 | ALDH1A1 (0.46) | FAAHMEN1ALDH1A1GAAMAPT | |
| SCHEMBL20542188 | 0.89 | FAAH (0.47) | FAAHS1PR1S1PR3MEN1MAPT | |
| Hydrochloric Acid SCHEMBL20541981 | 0.89 | HDAC1 (0.59) | HDAC1HTR2CMCHR1BACE1HDAC3 | |
| SCHEMBL20541859 | 0.87 | FAAH (0.45) | HDAC1MCHR1SUCNR1FAAHMEN1 | |
| SCHEMBL20542082 | 0.86 | MEN1 (0.51) | FAAHS1PR1S1PR3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |
| EP-3613735-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | Pusan National University Industry - University Cooperation Foundation (KR) | 2020-02-26 | — | — | EP | disclosed |
| WO-2018194372-A1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | 부산대학교 산학협력단 | 2018-10-25 | — | — | WO | disclosed |