Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | SORD | Q00796 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16855357 | 0.84 | PDE10A (0.49) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL27902619 | 0.84 | ACACB (0.46) | HRH3HRH4OPRD1MAP4K4SORD | |
| SCHEMBL3650736 | 0.82 | TRPV1 (0.46) | HRH3HRH4OPRD1SORDJAK3 | |
| SCHEMBL803732 | 0.82 | SIGMAR1 (0.45) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL16855303 | 0.82 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL16855474 | 0.81 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL27920434 | 0.81 | ACACB (0.43) | HRH3HRH4OPRD1MAP4K4SORD | |
| Hydrochloric Acid SCHEMBL18166972 | 0.81 | ALDH1A1 (0.39) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL18166971 | 0.81 | ALDH1A1 (0.39) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL20544120 | 0.81 | HRH3 (0.41) | HRH3HRH4OPRD1MAP4K4TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085700-B1 | NOVEL PIPERIDINE CARBOXAMIDE COMPOUND, PREPARATION METHOD, AND USAGE THEREOF | INST PHARMACOLOGY & TOXICOLOGY ACADEMY MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2018-10-31 | — | — | EP | claimed |
| US-11447463-B2 | Piperidine carboxamide compound, preparation method, and use thereof | Institute of Pharmacology and Toxicology Academy of Millitary Medical Sciences P.L.A. China (CN) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447463-B2 | Piperidine carboxamide compound, preparation method, and use thereof | HSF1, HSP90AB1, HSPD1 | MAPT 301/4885ALDH1A1 936/4885LMNA 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.